Preparation and characterization of novel poly(vinyl ester resin) monoliths

被引:20
作者
Yang, Gengliang [1 ,2 ]
Liu, Haiyan [1 ]
Bai, Ligai [1 ]
Jiang, Mingming [1 ]
Zhu, Tao [1 ]
机构
[1] Hebei Univ, Coll Pharm, Baoding 071002, Peoples R China
[2] Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
关键词
vinyl ester resin; monolith column; HPLC; preparation; characterization;
D O I
10.1016/j.micromeso.2007.10.009
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
We introduced a new monolithic column for H PLC. The monolithic column was prepared using vinyl ester resin not only as the monomer but also as the crosslinking agent based. The main factors affecting the porous structure of vinyl ester (VE) resin monolithic columns were investigated. By varying the porogen solvent and the amount of initiator, different porous structure could be obtained. In order to evaluate the mechanical stability of the column material, the pressure drop across the column was measured in different flow-rates. The pressure drop was a linear function of flow rate and the regression factor R was 0.9994, indicating a laminar flow regime. Moreover, the load of hydroxyl groups-the active group of the monolithic column was investigated. The average loading was 10.4 mmol g(-1). Moreover, other characteristics, such as IR and HPLC-MS was used as the detection for the structure of the monomer, a mercury porosimeter and thermal analysis measurements were used to determine pore size distribution and thermal properties of the monolith, respectively. Finally, using phenol, resorcinol and catechol as the test compounds, a normal-phase character of the VE resin monolith was evident. (C) 2007 Published by Elsevier Inc.
引用
收藏
页码:351 / 356
页数:6
相关论文
共 22 条
[1]   Polymeric monolithic materials: Syntheses, properties, functionalization and applications [J].
Buchmeiser, Michael R. .
POLYMER, 2007, 48 (08) :2187-2198
[2]  
Gao J., 1989, CHINESE J CATAL, V10, P422
[3]   Stability and repeatability of capillary columns based on porous monoliths of poly(butyl methacrylate-co-ethylene dimethacrylate) [J].
Geiser, Laurent ;
Eeltink, Sebastiaan ;
Svec, Frantisek ;
Frechet, Jean M. J. .
JOURNAL OF CHROMATOGRAPHY A, 2007, 1140 (1-2) :140-146
[4]   In situ functionalization of N-acryloxysuccinimide-based monolith for reversed-phase electrochromatography [J].
Guerrouache, Mohamed ;
Carbonnier, Benjamin ;
Vidal-Madjar, Claire ;
Millot, Marie-Claude .
JOURNAL OF CHROMATOGRAPHY A, 2007, 1149 (02) :368-376
[5]  
Liang YC, 1997, J POLYM SCI POL CHEM, V35, P2631, DOI 10.1002/(SICI)1099-0518(19970930)35:13<2631::AID-POLA10>3.0.CO
[6]  
2-C
[7]   Chromatographic separation of proteins on metal immobilized iminodiacetic acid-bound molded monolithic rods of macroporous poly(glycidyl methacrylate-co-ethylene dimethacrylate) [J].
Luo, QZ ;
Zou, HF ;
Xiao, XZ ;
Guo, Z ;
Kong, L ;
Mao, XQ .
JOURNAL OF CHROMATOGRAPHY A, 2001, 926 (02) :255-264
[8]   Current status of unsaturated polyester resins [J].
Malik, M ;
Choudhary, V ;
Varma, IK .
JOURNAL OF MACROMOLECULAR SCIENCE-REVIEWS IN MACROMOLECULAR CHEMISTRY AND PHYSICS, 2000, C40 (2-3) :139-165
[9]  
MILLEVILLE BA, 1990, 45 ANN C COMP I SOC
[10]  
Sands J. M., 2001, Clean Products and Processes, V2, P0228, DOI DOI 10.1007/S100980000089