Palladium-Catalyzed Intermolecular C(sp3)-H Amidation

被引：221

作者：

Iglesias, Alvaro ^{[2
]}

Alvarez, Rosana ^{[1
]}

de Lera, Angel R. ^{[1
]}

Muniz, Kilian ^{[2
,3
]}

机构：

[1] Univ Vigo, Dept Organ Chem, Vigo 36315, Spain

[2] Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain

[3] Catalan Inst Res & Adv Studies ICREA, Barcelona 08010, Spain

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 09期

关键词：

amidation; C?H activation; homogeneous catalysis; oxidation; palladium; C-H AMINATION; FORMING REDUCTIVE ELIMINATION; AEROBIC OXIDATIVE AMINATION; TERMINAL ALKENES; BOND-FORMATION; MECHANISM; DIAMINATION; REACTIVITY; COMPLEXES; CARBON;

D O I：

10.1002/anie.201108351

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Dual capacity: A new palladium-catalyzed intermolecular sequence consisting of the C-H activation and amidation of methyl groups relies on N-fluorobis(phenylsulfonyl)imide (NFSI) as both the oxidant and the nitrogen source. The reaction provides the corresponding arylamines as bissulfonimides along with HF as the only by-product. Both experimental and computational results suggest the involvement of a monomeric palladium(IV) intermediate. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：2225 / 2228

页数：4

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