Frequency of Thyroid Disorder in Pregnant Females in Tertiary Care Hospitals

Background: Thyroid dysfunction during pregnancy has been an important area of research due to its imminent in maternal and fetal outcome. Literature showed a wide range of hypothyroidism during pregnancy in Asian population. Aim:To find the rate of thyroid disorder duringpregnancy among the females presentingfor antenatal check-up in a tertiary-care hospital. Methods: This Cross sectional study was done at Department of Gynacology Lahore General Hospital, Lahore for 6 months. Sample size of 360 patients included and assessed for thyroid hormone levels. Blood sample of pregnant female was sent to laboratory of the hospital to note the level of TSH, free T3 & free T4 in blood. Reports were assessed and if levels were deranged, then thyroid dysfunction was noted. Results: The mean age of pregnant females was 26.63 +/- 7.41years and the gestational mean age of females was 19.64 +/- 6.88 weeks. Prevalence of thyroid disorder in this study was 159 (44.2%) out of 360 pregnant females. Among thyroid dysfunction cases, 159 (44.2%) pregnant females had thyroid dysfunction and 201 (55.8%) had euthyroid. Out of 159 positive females, subclinical hypothyroidism was observed in 107 (67.3%) while subclinical hyperthyroidism in 52(32.7%) with poor obstetrical history. Conclusions: This study concludes that hypothyroidism is high in pregnancy (67.5%). Most of these females had subclinical hypothyroidism.