Twin studies for the analysis of heritability of infections diseases

被引：9
作者：
Jepson, A [1 ]
机构：
[1] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England
来源：
BULLETIN DE L INSTITUT PASTEUR | 1998年 / 96卷 / 02期
基金：
英国惠康基金;
关键词：
twin; heritability; infectious disease; susceptibility; review;
D O I：
10.1016/S0020-2452(98)80001-8
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The important contribution made by twin studies to understanding the mechanisms of complex polygenic disorders is being increasingly recognized. That susceptibility to infectious diseases may have a heritable component is a concept that is gaining wider acceptance: twin studies have provided valuable support for this hypothesis. Recent twin studies have provided insights into mechanisms of disease pathogenesis and are currently also being used for gene mapping.
引用
收藏
页码：71 / 81
页数：11
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