Combination inhibitor strategies targeting KRAS effector signaling in KRAS-mutant pancreatic cancer.

被引：0
|
作者：
Ozkan-Dagliyan, Irem [1 ]
Goodwin, Craig M. [1 ]
Bryant, Kirsten L. [1 ]
George, Samuel D. [1 ]
Lucas, Kelly [1 ]
Gautam, Prson [2 ]
Wennerberg, Krister [2 ]
Cox, Adrienne D. [1 ]
Der, Channing J. [1 ]
机构：
[1] Univ N Carolina, Chapel Hill, NC 27515 USA
[2] Inst Mol Med Finland, Helsinki, Finland
来源：
MOLECULAR CANCER RESEARCH | 2020年 / 18卷 / 05期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
B31
引用
收藏
页码：68 / 68
页数：1
相关论文
共 50 条
  • [31] Targeting KRAS-regulated metabolic activities in pancreatic cancer.
    Bryant, Kirsten L.
    Hobbs, G. Aaron
    Der, Channing J.
    MOLECULAR CANCER RESEARCH, 2020, 18 (05) : 21 - 22
  • [32] Targeting KRAS-Mutant Non-Small Cell Lung Cancer with the Hsp90 Inhibitor Ganetespib
    Acquaviva, Jaime
    Smith, Donald L.
    Sang, Jim
    Friedland, Julie C.
    He, Suqin
    Sequeira, Manuel
    Zhang, Chaohua
    Wada, Yumiko
    Proia, David A.
    MOLECULAR CANCER THERAPEUTICS, 2012, 11 (12) : 2633 - 2643
  • [33] Evaluating a role for Rac1-PAK1 signaling in promoting the growth of KRAS-mutant pancreatic cancer
    Baker, Nicole M.
    LoBello, Janine
    Han, Haiyong
    Yin, Holly
    Yeh, Jen Jen
    Der, Channing J.
    MOLECULAR CANCER RESEARCH, 2014, 12
  • [34] A combinatorial strategy for treating KRAS-mutant lung cancer
    Eusebio Manchado
    Susann Weissmueller
    John P. Morris
    Chi-Chao Chen
    Ramona Wullenkord
    Amaia Lujambio
    Elisa de Stanchina
    John T. Poirier
    Justin F. Gainor
    Ryan B. Corcoran
    Jeffrey A. Engelman
    Charles M. Rudin
    Neal Rosen
    Scott W. Lowe
    Nature, 2016, 534 : 647 - 651
  • [35] DUAL CHECKPOINT ABROGATION IS SYNERGISTIC IN KRAS-MUTANT CANCER
    不详
    CANCER DISCOVERY, 2015, 5 (09) : 903 - 903
  • [36] A combinatorial strategy for treating KRAS-mutant lung cancer
    Manchado, Eusebio
    Weissmueller, Susann
    Morris, John P.
    Chen, Chi-Chao
    Wullenkord, Ramona
    Lujambio, Amaia
    de Stanchina, Elisa
    Poirier, John T.
    Gainor, Justin F.
    Corcoran, Ryan B.
    Engelman, Jeffrey A.
    Rudin, Charles M.
    Rosen, Neal
    Lowe, Scott W.
    NATURE, 2016, 534 (7609) : 647 - +
  • [37] Hope for targeted treatment of KRAS-mutant lung cancer
    Crisp, Alisa
    EXPERT REVIEW OF ANTICANCER THERAPY, 2013, 13 (02) : 121 - 121
  • [38] Uncovering mechanisms of immune evasion in a novel immunogenic model of KRAS-mutant lung cancer.
    Boumelha, Jesse
    de Carne, Sophie
    Mugarza, Edurne
    Romero-Clavijo, Pablo
    Molina-Arcas, Miriam
    Downward, Julian
    CANCER RESEARCH, 2021, 81 (13)
  • [39] Development of siRNA Payloads to Target KRAS-Mutant Cancer
    Yuan, Tina L.
    Fellmann, Christof
    Lee, Chih-Shia
    Ritchie, Cayde D.
    Thapar, Vishal
    Lee, Liam G.
    Hsu, Dennis J.
    Grace, Danielle
    Carver, Joseph O.
    Zuber, Johannes
    Luo, Ji
    McCormick, Frank
    Lowe, Scott W.
    CANCER DISCOVERY, 2014, 4 (10) : 1182 - 1197
  • [40] Implication of targeting YAP1 in KRAS-mutant lung cancer cells.
    Shimomura, Iwao
    Yamamoto, Yusuke
    Tada, Yuji
    Tatsumi, Koichiro
    Ochiya, Takahiro
    MOLECULAR CANCER RESEARCH, 2020, 18 (08) : 39 - 40
12345