Small-sized copolymeric nanoparticles for tumor penetration and intracellular drug release

被引：10

作者：

Zhu, Chun-Nan ^{[1
,2
]}

Zang, Liu-Yuan ^{[1
,2
]}

Zheng, Dong-Yun ^{[1
,2
]}

Cao, Hui-Min ^{[1
,2
]}

Liu, Xiao-Jun ^{[1
,2
]}

机构：

[1] South Cent Univ Nationalities, Coll Biomed Engn, Hubei Key Lab Med Informat Anal & Tumor Diag & Tr, Wuhan 430074, Peoples R China

[2] South Cent Univ Nationalities, Key Lab Cognit Sci, State Ethn Affairs Commiss, Wuhan 430074, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 13期

关键词：

POLYMERIC MICELLES; EFFICIENCY; SYSTEMS;

D O I：

10.1039/c9cc09716c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Poor solid-tumor penetration of nanocarriers limits the drug efficacy. Herein, small-sized copolymeric nanoparticles are prepared for delivering the chemotherapeutic drug DOX into solid tumors deeply and releasing the drug effectively. These small-sized copolymeric nanoparticles represent substantial potential for clinical translation.

引用

页码：2000 / 2003

页数：4

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