Identification and functional characterization of novel genetic variants of the human multidrug resistance protein 2 (MRP2/ABCC2)

被引：0
|
作者：
Koelz, C. [1 ,2 ]
Schaeffeler, E. [1 ,2 ]
Tremmel, R. [1 ,2 ]
Winter, S. [1 ,2 ]
Klein, K. [1 ,2 ]
Zanger, U. M. [1 ,2 ]
Schwab, M. [1 ,2 ,3 ,4 ,5 ]
Nies, A. T. [1 ,2 ]
机构：
[1] Dr Margarete Fischer Bosch Inst Clin Pharmacol, Stuttgart, Germany
[2] Univ Tubingen, Tubingen, Germany
[3] Univ Tubingen, Dept Clin Pharmacol, Tubingen, Germany
[4] Univ Tubingen, Dept Pharm, Tubingen, Germany
[5] Univ Tubingen, Dept Biochem, Tubingen, Germany
来源：
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY | 2019年 / 392卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
61
引用
收藏
页码：S17 / S17
页数：1
相关论文
共 50 条
  • [31] Functional characterization of protein variants of the human multidrug transporter ABCC2 by a novel targeted expression system in fibrosarcoma cells
    Arlanov, Rudolf
    Porter, Andrew
    Strand, Dennis
    Brough, Rachel
    Karpova, Darja
    Kerb, Reinhold
    Wojnowski, Leszek
    Schwab, Matthias
    Lang, Thomas
    HUMAN MUTATION, 2012, 33 (04) : 750 - 762
  • [32] The role of protein synthesis and degradation in the post-transcriptional regulation of rat multidrug resistance-associated protein 2 (Mrp2, Abcc2)
    Jones, BR
    Li, W
    Cao, J
    Hoffman, TA
    Gerk, PM
    Vore, M
    MOLECULAR PHARMACOLOGY, 2005, 68 (03) : 701 - 710
  • [33] Selenium-dependent and -independent transport of arsenic by the human multidrug resistance protein 2 (MRP2/ABCC2): implications for the mutual detoxification of arsenic and selenium
    Carew, Michael W.
    Leslie, Elaine M.
    CARCINOGENESIS, 2010, 31 (08) : 1450 - 1455
  • [34] Absolute quantification of multidrug resistance-associated protein 2 (MRP2/ABCC2) using liquid chromatography tandem mass spectrometry
    Li, Na
    Nemirovskiy, Olga V.
    Zhang, Yiqun
    Yuan, Haodan
    Mo, Jianming
    Ji, Chengjie
    Zhang, Bo
    Brayman, Timothy G.
    Lepsy, Christopher
    Heath, Timothy G.
    Lai, Yurong
    ANALYTICAL BIOCHEMISTRY, 2008, 380 (02) : 211 - 222
  • [35] Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2) Haplotypes Significantly Affect the Pharmacokinetics of Tacrolimus in Kidney Transplant Recipients
    Ken Ogasawara
    Shripad D. Chitnis
    Reginald Y. Gohh
    Uwe Christians
    Fatemeh Akhlaghi
    Clinical Pharmacokinetics, 2013, 52 : 751 - 762
  • [36] Microrna Let-7a-5p Controls the Expression of the Multidrug Resistance-Associated Protein 2 (ABCC2/MRP2).
    Balasubramaniyan, Natarajan
    Devereaux, Michael W.
    Sokol, Ronald J.
    Suchy, Frederick J.
    HEPATOLOGY, 2018, 68 : 874A - 874A
  • [37] The apical conjugate efflux pump ABCC2 (MRP2)
    Nies, Anne T.
    Keppler, Dietrich
    PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2007, 453 (05): : 643 - 659
  • [38] Role of multidrug resistance protein 2 (MRP2, ABCC2) in alkylating agent detoxification:: MRP2 potentiates glutathione S-transferase A1-1-mediated resistance to chlorambucil cytotoxicity
    Smitherman, PK
    Townsend, AJ
    Kute, TE
    Morrow, CS
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2004, 308 (01) : 260 - 267
  • [39] MRP2 (ABCC2) and cisplatin sensitivity in hepatocytes and human ovarian carcinoma
    Guminski, AD
    Balleine, RL
    Chiew, YE
    Webster, LR
    Tapner, M
    Farrell, GC
    Harnett, PR
    deFazio, A
    GYNECOLOGIC ONCOLOGY, 2006, 100 (02) : 239 - 246
  • [40] Interindividual variability of multidrug resistance protein 2 (ABCC2) expression in human liver: impact of ABCC2 polymorphisms
    Lang, T.
    Toliat, M.
    Goedtel-Armbrust, U.
    Klein, K.
    Zanger, U. M.
    Wojnowski, L.
    Fromm, M. F.
    Glaeser, H.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2009, 379 : 93 - 93
12345