First partial characterisation of small ruminant lentiviruses from Greece

被引：16

作者：

Angelopoulou, K

Karanikolaou, K

Papanastasopoulou, M

Koumpati-Artopiou, M

Vlemmas, I

Papadopoulos, O

Koptopoulos, G ^{[1
]}

机构：

[1] Aristotle Univ Thessaloniki, Sch Vet Med, Lab Microbiol & Infect Dis, GR-54006 Thessaloniki, Greece

[2] Aristotle Univ Thessaloniki, Sch Vet Med, Toxicol & Biochem Lab, GR-54006 Thessaloniki, Greece

[3] Aristotle Univ Thessaloniki, Sch Vet Med, Pathol Lab, GR-54006 Thessaloniki, Greece

来源：

VETERINARY MICROBIOLOGY | 2005年 / 109卷 / 1-2期

关键词：

SRLV; CAEV; MVV; gag; nucleotide sequence;

D O I：

10.1016/j.vetmic.2005.04.025

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Small ruminant lentivirus (SRLV) infections are widespread in Greece, but SRLVs have never been isolated and characterized. In this study, we present the sequence of a 574-nucleotide (191-amino acid) region of the gag gene of SRLV strains from four sheep and one goat from a single geographic area of Greece. All five sequences appeared to be closely related at both nucleotide (2.1-14.2% variation) and deduced amino acid (1.6-4.2% variation) level. Greek SRLV strains were closer to ovine prototypic strains (average divergence 16.8%) than to the caprine strain CAEV-Co (21% divergence). By amino acid composition, the Greek SRLVs were on the average more than twice as distant from CAEV-Co as from other ovine strains. Phylogenetic analysis suggested that Greek strains segregate into a unique group, separate from, but related to, other ovine prototype sequences. (C) 2005 Elsevier B.V. All rights reserved.

引用

页码：1 / 9

页数：9

共 28 条

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[2] Conserved sequence motifs involving the tat reading frame of Brazilian caprine lentiviruses indicate affiliations to both caprine arthritis-encephalitis virus and visna-maedi virus [J].