Label-free Measurement of DNA Oligomer Binding Using a Highly-sensitive Photonic Crystal Biosensor

被引:0
|
作者
Guo, Yunbo [1 ,2 ]
Ye, Jing Yong [3 ]
Thomas, Thommey P. [2 ]
Baker, James R., Jr. [2 ]
Norris, Theodore B. [1 ,2 ]
机构
[1] Univ Michigan, Ctr Ultrafast Opt Sci, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Michigan Nanotechnol, Inst Med & Biol Sci, Ann Arbor, MI 48109 USA
[3] Univ Texas San Antonio, Dept Biomed Engn, San Antonio, TX 78249 USA
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中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
With a highly sensitive one dimensional photonic crystal biosensor, we have demonstrated quantitative real-time label-free detection of DNA oligomers, including binding to protein, concentration detection limits, and base-mismatched hybridization. (C) 2010 Optical Society of America
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页数:2
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