Quality-of-life evaluation in chronic wounds: comparative analysis of three disease-specific questionnaires

被引:12
作者
Augustin, Matthias [1 ]
Baade, Katrin [1 ]
Heyer, Kristina [1 ]
Price, Patricia E. [2 ]
Herberger, Katharina [1 ]
Wild, Thomas [3 ]
Engelhardt, Michael [4 ]
Debus, Eike S. [5 ]
机构
[1] Univ Med Ctr Hamburg Eppendorf UKE, Inst Hlth Serv Res Dermatol & Nursing IVDP, Martinistr 52, D-20246 Hamburg, Germany
[2] Cardiff Univ, Sch Med, Dept Wound Healing, Cardiff, S Glam, Wales
[3] Dessau Med Ctr, Dept Dermatol Venereol Allergol & Immunol, Dessau, Germany
[4] Mil Hosp Ulm, Dept Vasc & Endovasc Surg, Ulm, Germany
[5] Univ Med Ctr Hamburg Eppendorf UKE, Univ Heart Ctr, Hamburg, Germany
关键词
Health-related quality of life; Outcomes research; Patient-reported outcomes; Questionnaire; Wounds; VALIDATION; INSTRUMENTS;
D O I
10.1111/iwj.12803
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
The study directly compared the feasibility and performance of three instruments measuring health-related quality of life (HRQoL) in chronic ulcers: the Freiburg Life Quality Assessment for wounds (FLQA-w), the Cardiff Wound Impact Schedule (CWIS) and the Wurzburg Wound Score (WWS). The questionnaires were evaluated in a randomly assigned order in a longitudinal observational study of leg ulcer patients. Psychometric properties (internal consistency, responsiveness and construct validity) were analysed. Patient acceptance was recorded. Analysis of n = 154 patients revealed good internal consistency (Cronbach's alpha 085) for all instruments. There were minor floor effects in all questionnaires (<1%) and some ceiling effects in the CWIS. Construct validity was satisfactory, for example, correlation with EuroQoL-5D was r = 070 in the FLQA-w, r = 047/067/068 in the CWIS dimensions and r = 060 in the WWS. The proportion of missing values was higher in the CWIS, and overall patient acceptance was highest in the FLQA-w for wounds (54% best preferences) and lowest in the WWS (14%). In conclusion, the FLQA-w, the CWIS and the WWS are reliable, sensitive and valid instruments for the assessment of HRQoL in leg ulcers. However, they show differences in clinical feasibility and patient acceptance.
引用
收藏
页码:1299 / 1304
页数:6
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