A pilot randomized clinical trial of Brief Behavioral Treatment for Insomnia to reduce problematic cannabis use among trauma-exposed young adults
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作者:
Short, Nicole A.
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Florida State Univ, Dept Psychol, 1107 W Call St, Tallahassee, FL 32306 USA
Univ N Carolina, Dept Anesthesiol, Chapel Hill, NC 27515 USAFlorida State Univ, Dept Psychol, 1107 W Call St, Tallahassee, FL 32306 USA
Short, Nicole A.
[1
,2
]
Zvolensky, Michael J.
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Univ Houston, Dept Psychol, Houston, TX USA
MD Anderson Canc Ctr, Houston, TX USAFlorida State Univ, Dept Psychol, 1107 W Call St, Tallahassee, FL 32306 USA
Zvolensky, Michael J.
[3
,4
]
Schmidt, Norman B.
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机构:
Florida State Univ, Dept Psychol, 1107 W Call St, Tallahassee, FL 32306 USAFlorida State Univ, Dept Psychol, 1107 W Call St, Tallahassee, FL 32306 USA
Schmidt, Norman B.
[1
]
机构:
[1] Florida State Univ, Dept Psychol, 1107 W Call St, Tallahassee, FL 32306 USA
[2] Univ N Carolina, Dept Anesthesiol, Chapel Hill, NC 27515 USA
Background: Insomnia symptoms may be an important etiological factor for substance use disorders; however, whether improving sleep leads to reductions in problematic substance use among at-risk populations remains unclear. Method: As such, the current pilot study used a randomized controlled design to test the effects of Brief Behavioral Treatment for Insomnia (BBTI) against a waitlist control among a sample of trauma-exposed young adults with elevated insomnia symptoms who regularly use cannabis (N = 56). Results: Intent-to-treat multilevel modeling analyses indicated that BBTI may be more efficacious than waitlist control in reducing self-reported insomnia symptoms, with large effects three months post-treatment (d = 1.34). Further, our initial evidence suggested that BBTI resulted in reductions in cannabis-related problems with medium to large effects at three months post-treatment (d = 0.75). The current pilot analyses indicated BBTI also reduced cravings to use cannabis to reduce negative emotions in response to trauma cues with a large effect size. Conclusion: This pilot study suggests BBTI may be efficacious not only in improving insomnia symptoms among cannabis users but also in reducing cannabis-related problems and cravings over three months. Future research should replicate these results in a larger, fully powered sample with improved follow-up rates designed to test temporal mediation using multimethod assessments of insomnia symptoms and problematic cannabis use. Overall, BBTI may be a promising intervention for trauma-exposed cannabis users to improve sleep and reduce cannabis-related problems.
机构:
Seattle Childrens Res Inst, Ctr Clin & Translat Res, Seattle, WA 98101 USA
Univ Washington, Sch Med, Dept Pediat, Seattle, WA 98195 USASeattle Childrens Res Inst, Ctr Clin & Translat Res, Seattle, WA 98101 USA
Fladeboe, Kaitlyn M.
Scott, Samantha
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Seattle Childrens Res Inst, Ctr Clin & Translat Res, Seattle, WA 98101 USA
Univ Denver, Dept Psychol, Denver, CO 80208 USASeattle Childrens Res Inst, Ctr Clin & Translat Res, Seattle, WA 98101 USA
Scott, Samantha
Bradford, Miranda C.
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Seattle Childrens Res Inst, Ctr Clin & Translat Res, Seattle, WA 98101 USASeattle Childrens Res Inst, Ctr Clin & Translat Res, Seattle, WA 98101 USA
Bradford, Miranda C.
Ketterl, Tyler G.
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Univ Washington, Sch Med, Dept Pediat, Seattle, WA 98195 USA
Seattle Childrens Hosp, Ctr Canc & Blood Disorders, Seattle, WA USASeattle Childrens Res Inst, Ctr Clin & Translat Res, Seattle, WA 98101 USA
Ketterl, Tyler G.
Yi-Frazier, Joyce P.
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Seattle Childrens Res Inst, Ctr Clin & Translat Res, Seattle, WA 98101 USASeattle Childrens Res Inst, Ctr Clin & Translat Res, Seattle, WA 98101 USA
Yi-Frazier, Joyce P.
Rosenberg, Abby R.
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Seattle Childrens Res Inst, Ctr Clin & Translat Res, Seattle, WA 98101 USA
Univ Washington, Sch Med, Dept Pediat, Seattle, WA 98195 USA
Univ Washington, Sch Med, Dept Pediat, Div Bioeth Palliat Care, Seattle, WA 98195 USASeattle Childrens Res Inst, Ctr Clin & Translat Res, Seattle, WA 98101 USA
机构:
Boston Childrens Hosp, Dept Psychiat, Boston, MA USA
Boston Childrens Hosp, Dept Med, Boston, MA USA
Boston Childrens Hosp, Ctr Adolescent Subst Use & Addict Res, Boston, MA USA
Harvard Med Sch, Dept Pediat, Boston, MA 02115 USABoston Childrens Hosp, Dept Psychiat, Boston, MA USA
Knight, John R.
Sherritt, Lon
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Boston Childrens Hosp, Dept Med, Boston, MA USA
Boston Childrens Hosp, Ctr Adolescent Subst Use & Addict Res, Boston, MA USA
Harvard Med Sch, Dept Pediat, Boston, MA 02115 USABoston Childrens Hosp, Dept Psychiat, Boston, MA USA
Sherritt, Lon
Gibson, Erin Bray
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机构:
Boston Childrens Hosp, Dept Med, Boston, MA USA
Boston Childrens Hosp, Ctr Adolescent Subst Use & Addict Res, Boston, MA USA
Boston Childrens Hosp, Div Adolescent & Young Adult Med, 300 Longwood Ave,Mailstop 3189, Boston, MA 02115 USABoston Childrens Hosp, Dept Psychiat, Boston, MA USA
Gibson, Erin Bray
Levinson, Jordan A.
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Boston Childrens Hosp, Dept Med, Boston, MA USA
Boston Childrens Hosp, Ctr Adolescent Subst Use & Addict Res, Boston, MA USA
Boston Childrens Hosp, Div Adolescent & Young Adult Med, 300 Longwood Ave,Mailstop 3189, Boston, MA 02115 USABoston Childrens Hosp, Dept Psychiat, Boston, MA USA
Levinson, Jordan A.
Grubb, Laura K.
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Tufts Med Ctr, Dept Pediat, Floating Hosp Children, Boston, MA 02111 USABoston Childrens Hosp, Dept Psychiat, Boston, MA USA
Grubb, Laura K.
Samuels, Ronald C.
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Boston Childrens Hosp, Dept Med, Boston, MA USA
Harvard Med Sch, Dept Pediat, Boston, MA 02115 USA
Boston Childrens Hosp, Div Gen Acad Pediat, Boston, MA USABoston Childrens Hosp, Dept Psychiat, Boston, MA USA
Samuels, Ronald C.
Silva, Thomas
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East Boston Neighborhood Hlth Ctr, Boston, MA USABoston Childrens Hosp, Dept Psychiat, Boston, MA USA
Silva, Thomas
Vernacchio, Louis
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Boston Childrens Hosp, Dept Med, Boston, MA USA
Harvard Med Sch, Dept Pediat, Boston, MA 02115 USA
Boston Childrens Hosp, Div Gen Acad Pediat, Boston, MA USA
Longwood Pediat, Boston, MA USABoston Childrens Hosp, Dept Psychiat, Boston, MA USA
Vernacchio, Louis
Wornham, Wendy
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Boston Childrens Hosp, Dept Med, Boston, MA USA
Harvard Med Sch, Dept Pediat, Boston, MA 02115 USA
Lexington Pediat, Lexington, MA USABoston Childrens Hosp, Dept Psychiat, Boston, MA USA
Wornham, Wendy
Harris, Sion Kim
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Boston Childrens Hosp, Dept Med, Boston, MA USA
Boston Childrens Hosp, Ctr Adolescent Subst Use & Addict Res, Boston, MA USA
Harvard Med Sch, Dept Pediat, Boston, MA 02115 USA
Boston Childrens Hosp, Div Adolescent & Young Adult Med, 300 Longwood Ave,Mailstop 3189, Boston, MA 02115 USABoston Childrens Hosp, Dept Psychiat, Boston, MA USA
机构:
Syracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USASyracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USA
Scheer, Jillian R.
Behari, Kriti
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Syracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USASyracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USA
Behari, Kriti
Schwarz, Aubriana A.
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Syracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USASyracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USA
Schwarz, Aubriana A.
Cascalheira, Cory J.
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New Mexico State Univ, Dept Counseling & Educ Psychol, Las Cruces, NM 88003 USA
VA Puget Sound Hlth Care Syst, Seattle, WA 98108 USASyracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USA
Cascalheira, Cory J.
Helminen, Emily C.
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Syracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USASyracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USA
Helminen, Emily C.
Pirog, Sophia A.
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Syracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USASyracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USA
Pirog, Sophia A.
Jaipuriyar, Virinca
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Syracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USASyracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USA
Jaipuriyar, Virinca
Sullivan, Tami P.
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Yale Univ, Sch Med, Dept Psychiat, New Haven, CT 06501 USASyracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USA
Sullivan, Tami P.
Batchelder, Abigail W.
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Harvard Univ, Harvard Med Sch, Boston, MA 02114 USA
Massachusetts Gen Hosp, Dept Psychiat, Behav Med Program, Boston, MA 02114 USA
Fenway Hlth, Fenway Inst, Boston, MA 02115 USASyracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USA
Batchelder, Abigail W.
Jackson, Skyler D.
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Yale Sch Publ Hlth, Dept Social & Behav Sci, New Haven, CT 06501 USASyracuse Univ, Dept Psychol, 414 Huntington Hall, Syracuse, NY 13244 USA
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Columbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Johns Hopkins Bloomberg Sch Publ Hlth, Dept Mental Hlth, Baltimore, MD 21205 USAColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Kane, Jeremy C.
Sharma, Anjali
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Ctr Infect Dis Res Zambia, Lusaka, ZambiaColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Sharma, Anjali
Murray, Laura K.
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Johns Hopkins Bloomberg Sch Publ Hlth, Dept Mental Hlth, Baltimore, MD 21205 USAColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Murray, Laura K.
Chander, Geetanjali
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Johns Hopkins Univ, Sch Med, Baltimore, MD USAColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Chander, Geetanjali
Kanguya, Tukiya
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Ctr Infect Dis Res Zambia, Lusaka, ZambiaColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Kanguya, Tukiya
Skavenski, Stephanie
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Johns Hopkins Bloomberg Sch Publ Hlth, Dept Mental Hlth, Baltimore, MD 21205 USAColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Skavenski, Stephanie
Chitambi, Chipo
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Ctr Infect Dis Res Zambia, Lusaka, ZambiaColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Chitambi, Chipo
Lasater, Molly E.
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Johns Hopkins Bloomberg Sch Publ Hlth, Dept Mental Hlth, Baltimore, MD 21205 USAColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Lasater, Molly E.
Paul, Ravi
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Univ Zambia, Univ Teaching Hosp, Sch Med, Lusaka, ZambiaColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Paul, Ravi
Cropsey, Karen
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Univ Alabama Birmingham, Sch Med, Birmingham, AL USAColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Cropsey, Karen
Inoue, Sachi
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Columbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USAColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Inoue, Sachi
Bosomprah, Samuel
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Ctr Infect Dis Res Zambia, Lusaka, ZambiaColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Bosomprah, Samuel
Danielson, Carla Kmett
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Med Univ South Carolina, Dept Psychiat & Behav Sci, Charleston, SC 29425 USAColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Danielson, Carla Kmett
Chipungu, Jenala
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Ctr Infect Dis Res Zambia, Lusaka, ZambiaColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Chipungu, Jenala
Simenda, Francis
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Zambia Minist Hlth, Lusaka, ZambiaColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA
Simenda, Francis
Vinikoor, Michael J.
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Ctr Infect Dis Res Zambia, Lusaka, Zambia
Univ Alabama Birmingham, Sch Med, Birmingham, AL USAColumbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, 722 W 168th St,Room 519, New York, NY 10032 USA