Synthesis, structural characterization and biological activity against several human tumor cell lines of four rhenium(I) diseleno-ethers complexes: Re(CO)3Cl(PhSe(CH2)2SePh), Re(CO)3Cl(PhSe(CH2)3SePh), Re(CO)3Cl(HO2C-CH2Se(CH2)2SeCH2-CO2H) and Re(CO)3Cl(HO2C-CH2Se(CH2)3SeCH2-CO2H)

被引：27
|
作者：
Kermagoret, Anthony [1 ]
Morgant, Georges [1 ]
d'Angelo, Jean [1 ]
Tomas, Alain [2 ]
Roussel, Pascal [3 ]
Bastian, Gerard [4 ]
Collery, Philippe [5 ]
Desmaele, Didier [1 ]
机构：
[1] Univ Paris Sud, UMR CNRS 8076, Lab BioCIS, IFR 141,Fac Pharm, F-92296 Chatenay Malabry, France
[2] Univ Paris 05, UMR CNRS 8015, Lab Cristallog & RMN Biol, Fac Pharm, F-75005 Paris, France
[3] Ecole Natl Super Chim Lille, UMR CNRS 8181, Unite Catalyse & Chim Solide, F-59652 Villeneuve Dascq, France
[4] CHU Pitie Salpetriere, Pharmacol Lab, F-75013 Paris, France
[5] Soc Coordinat Rech Therapeut, F-20200 Algajola, France
来源：
POLYHEDRON | 2011年 / 30卷 / 02期
关键词：
Rhenium(I) complexes; Diseleno-ethers ligands; X-ray structures; Cytotoxicity; MTT; NUCLEAR MAGNETIC-RESONANCE; CRYSTAL-STRUCTURE; TRICARBONYL COMPLEXES; CYTOTOXICITY; COMPOUND; BEHAVIOR; LIGANDS;
D O I：
10.1016/j.poly.2010.10.026
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Four novel rhenium(I) diseleno-ethers complexes, namely Re(CO)(3)Cl(PhSe(CH2)(2)SePh) (5), Re(CO)(3)Cl(PhSe(CH2)(3)SePh-(6),Re(CO)(3)Cl(HO2C-CH2Se(CH2)(2)SeCH2-CO2H)(7) and Re(CO)(3)Cl(HO2C-CH2Se(CH2)(3)SeCH2-CO2H) (8), have been synthesized by reaction of Re(CO)(5)Cl with the corresponding bidentate ligands. Structures of 5 and 6 were established by single-crystal X-ray diffraction analysis. Complexes 7 and 8 were identified by elemental analysis, H-1 NMR-, IR- and mass spectroscopy. The antiproliferative activity of these complexes against four solid human tumor cells was determined. The water-soluble disodium salts of complexes 7 and 8 exhibited marked activities against MCF-7 breast cancer cells. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：347 / 353
页数：7
相关论文
共 50 条
  • [31] Evolution of the structures and magnetic properties of the manganese dicarboxylates, Mn2(CO2(CH2)nCO2)(OH)2 and Mn4(CO2(CH2)nCO2)3(OH)2
    Saines, Paul J.
    Jain, Prashant
    Cheetham, Anthony K.
    CHEMICAL SCIENCE, 2011, 2 (10) : 1929 - 1939
  • [32] Infrared and NMR spectra of arylsulphonamides, 4-X-C6H4SO2NH2 and i-X, j-YC6H3SO2NH2 (X = H; CH3; C2H5; F; Cl; Br; I or NO2 and i-X, j-Y = 2,3-(CH3)2; 2,4-(CH3)2; 2,5(CH3)2; 2-CH3, 4-Cl; 2-CH3, 5-Cl; 3-CH3, 4-Cl; 2,4-Cl2 or 3,4-Cl2)
    Gowda, BT
    Jyothi, K
    D'Souza, JD
    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION A-A JOURNAL OF PHYSICAL SCIENCES, 2002, 57 (12): : 967 - 973
  • [33] Synthesis and crystal structure of the [Re2(CH3COO)2Cl4((CH3)2NCOCH3)2] complex
    Mel'nik, SG
    Filinchuk, YE
    Shtemenko, AV
    RUSSIAN JOURNAL OF COORDINATION CHEMISTRY, 2004, 30 (11) : 786 - 791
  • [34] New Heterometallic Co(III) Pivalate Complexes with 1,3-(CH2)3(NH2)2
    Lutsenko, I. A.
    Nelyubina, Yu, V
    Primakov, P., V
    Ivanova, T. M.
    Maslakov, K., I
    Khoroshilov, A., V
    Kiskin, M. A.
    Sidorov, A. A.
    Eremenko, I. L.
    RUSSIAN JOURNAL OF COORDINATION CHEMISTRY, 2019, 45 (11) : 759 - 766
  • [35] Hydrogen bonding principles in inclusion compounds of triphenylsilanol and pyrrolidine: Synthesis and structural features of [(Ph3SiOH)4•HN(CH2)4] and [Ph3SiOH•HN(CH2)4•CH3CO2H]
    Bauer, Jonathan O.
    Strohmann, Carsten
    JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2015, 797 : 52 - 56
  • [36] Synthesis and Crystal Structure of the [Re2(CH3COO)2Cl4((CH3)2NCOCH3)2] Complex
    S. G. Mel'nik
    Ya. E. Filinchuk
    A. V. Shtemenko
    Russian Journal of Coordination Chemistry, 2004, 30 : 786 - 791
  • [37] CRYSTAL-STRUCTURES, VIBRATIONAL-SPECTRA, AND NORMAL-COORDINATE ANALYSES OF THE STEREOISOMERIC TRIFLUOROTRICHLOROPLATINATES(IV),FAC-[(C5H5N)(2)CH2][PTF3CL3]CENTER-DOT-0.5(CH3)(2)CO AND MER-[(C5H5N)(2)CH2][PTF3CL3]
    BRUHN, C
    DREWS, HH
    MEYNHARDT, B
    PREETZ, W
    ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 1995, 621 (03): : 373 - 380
  • [38] Synthesis of the dinuclear halogeno-bridged complexes [Re2(μ-X)2(CO)6(CH3CN)2],(X = Cl, Br)
    Carballo, R
    García-Martínez, E
    Pereiras-Gabián, G
    Vázquez-López, EM
    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2003, 58 (10): : 1021 - 1023
  • [39] Reductive carbonylation route to Co(0) and Co(I) carbonyl complexes containing bridging, chelating and cleaved diphosphazanes.: Structures of [Co(CO){P(OR)2(NHMe)}2{P(O)(OR)2}{P(H)(OR′)2}] (R = CH2CF3, R′ = CH2CH3), [Co2(CO)2{μ-MeN{P(OR)2}2}3] (R = CH2CF3), and [Co(CO){η2-MeN{P(OR)2}2}2][CoCl3(OC4H8)] (R = Ph)
    Ganesan, M
    Krishnamurthy, SS
    Nethaji, M
    JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1998, 570 (02) : 247 - 254
  • [40] Palladium(I) and palladium(II) unsaturated carboxylate complexes with small molecules: Synthesis and X-ray structure of Pd4(μ-CO)4(μ-trans-CH3CH=CHCO2)4 and Pd4(μ-NO)2(μ-CH2=C(CH3)CO2)6
    Shishilov, Oleg N.
    Ankudinova, Polina V.
    Nikitenko, Elena V.
    Churakov, Andrei V.
    Garbuzova, Irina A.
    Akhmadullina, Nailya S.
    Minaeva, Natalia A.
    Demina, Lyudmila I.
    Efimenko, Inessa A.
    JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2014, 767 : 112 - 119
12345