Quantifying the Short-term Effects of Deep Brain Stimulation Surgery on Bradykinesia in Parkinson's Disease Patients

被引:0
作者
Delrobaei, Mehdi [1 ]
Parrent, Andrew [1 ]
Jog, Mandar [1 ]
Rahimi, Fariborz [2 ]
Tran, Stephanie [3 ]
Ognjanovic, Kristina [3 ]
Gilmore, Greydon [3 ]
McIssac, Kenneth [4 ]
机构
[1] London Hlth Sci Ctr, London, ON, Canada
[2] Bonab Univ, Dept Elect & Comp Engn, Bonab, East Azerbaijan, Iran
[3] Western Univ, Dept Clin Neurol Sci, London, ON, Canada
[4] Western Univ, Dept Elect & Comp Engn, London, ON, Canada
来源
2014 21TH IRANIAN CONFERENCE ON BIOMEDICAL ENGINEERING (ICBME) | 2014年
关键词
Parkinson's disease; deep brain stimulation; bradykinesia; slowness of movement; objective measures; MONITORING-SYSTEM; QUANTIFICATION;
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Clinical scale-based follow-up of patients undergoing bilateral subthalamic deep brain stimulation (STN-DBS) surgery has shown inconsistent effects on bradykinesia in Parkinson's disease patients. Furthermore, quantitative assessment of STN-DBS effect on bradykinesia has not been fully explored yet. Our group uses multisensory kinematic technologies to study short-term and long-term DBS effects on Parkinson's disease. In this paper we present a kinematic analysis of the short term (3 month) effects of STN-DBS on bradykinesia in five PD patients and compare the results with data obtained from healthy age-matched controls.
引用
收藏
页码:224 / 228
页数:5
相关论文
共 13 条
[1]   On the use of low-cost computer peripherals for the assessment of motor dysfunction in Parkinson's disease- Quantification of bradykinesia using target tracking tasks [J].
Allen, D. P. ;
Playfer, J. R. ;
Aly, N. M. ;
Duffey, P. ;
Heald, A. ;
Smith, S. L. ;
Halliday, D. M. .
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, 2007, 15 (02) :286-294
[2]   An EMG-Based System for Continuous Monitoring of Clinical Efficacy of Parkinson's Disease Treatments [J].
Askari, Sina ;
Zhang, Mo ;
Won, Deborah S. .
2010 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), 2010, :98-101
[3]  
Dai H., 2013, QUANTIFY NEUROLOGICA, V13, P3193
[4]  
Dai HD, 2013, I CON ADV BIOMED ENG, P77, DOI 10.1109/ICABME.2013.6648851
[5]   A Novel Glove Monitoring System Used to Quantify Neurological Symptoms During Deep-Brain Stimulation Surgery [J].
Dai, Houde ;
Otten, Bernward ;
Mehrkens, Jan Hinnerk ;
D'Angelo, L. T. ;
Lueth, Tim C. .
IEEE SENSORS JOURNAL, 2013, 13 (09) :3193-3202
[6]   Rating scales as outcome measures for clinical trials in neurology: problems, solutions, and recommendations [J].
Hobart, Jeremy C. ;
Cano, Stefan J. ;
Zajicek, John P. ;
Thompson, Alan J. .
LANCET NEUROLOGY, 2007, 6 (12) :1094-1105
[7]   Improvement in a quantitative measure of bradykinesia after microelectrode recording in patients with Parkinson's disease during deep brain stimulation surgery [J].
Koop, Mandy Miller ;
Andrzejewski, Amy ;
Hill, Bruce C. ;
Heit, Gary ;
Bronte-Stewart, Helen M. .
MOVEMENT DISORDERS, 2006, 21 (05) :673-678
[8]   Micro subthalamotomy:: An immediate predictor of long-term subthalamic stimulation efficacy in Parkinson disease [J].
Maltete, David ;
Derrey, Stephane ;
Chastan, Nathalie ;
Debono, Bertrand ;
Gerardin, Emmanuel ;
Freger, Pierre ;
Mihout, Bruno ;
Menard, Jean Francois ;
Hannequin, Didier .
MOVEMENT DISORDERS, 2008, 23 (07) :1047-1050
[9]   The impact on Parkinson's disease of electrical parameter settings in STN stimulation [J].
Moro, E ;
Esselink, RJA ;
Xie, J ;
Hommel, M ;
Benabid, AL ;
Pollak, P .
NEUROLOGY, 2002, 59 (05) :706-713
[10]   Assessing bradykinesia in Parkinsonian disorders [J].
Pal, Gian ;
Goetz, Christopher G. .
FRONTIERS IN NEUROLOGY, 2013, 4