Copper(II) Oxide Catalyzed Ligand-Free Coupling Reaction of Heteroarenes with Bromoalkynes

被引：18
作者：
Das, Biswanath [1 ]
Reddy, Gandolla Chinna [1 ]
Balasubramanyam, Penagaluri [1 ]
Salvanna, N. [1 ]
机构：
[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500607, Andhra Pradesh, India
来源：
SYNTHESIS-STUTTGART | 2011年 / 05期
关键词：
coupling reaction; ligand-free conditions; copper(II) oxide; N-alkynylheteroarene; N-(2-bromovinyl)heteroarene; ALPHA-AMINO PHOSPHONATES; IMIDAZOLES; YNAMIDES; YNAMINES; SALTS;
D O I：
10.1055/s-0030-1258403
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The coupling reaction of imidazoles and pyrazoles with bromoacetylenes has efficiently been carried out under ligand-free conditions in the presence of copper(II) oxide as the catalyst using potassium hydroxide in 1,4-dioxane at 80 degrees C. The method is a simpler access to N-alk-1-ynyl- and/or N-(2-bromovinyl)-substituted heteroarenes.
引用
收藏
页码：816 / 820
页数：5
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