Copper(II) Oxide Catalyzed Ligand-Free Coupling Reaction of Heteroarenes with Bromoalkynes

被引：18

作者：

Das, Biswanath ^{[1
]}

Reddy, Gandolla Chinna ^{[1
]}

Balasubramanyam, Penagaluri ^{[1
]}

Salvanna, N. ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500607, Andhra Pradesh, India

来源：

SYNTHESIS-STUTTGART | 2011年 / 05期

关键词：

coupling reaction; ligand-free conditions; copper(II) oxide; N-alkynylheteroarene; N-(2-bromovinyl)heteroarene; ALPHA-AMINO PHOSPHONATES; IMIDAZOLES; YNAMIDES; YNAMINES; SALTS;

D O I：

10.1055/s-0030-1258403

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The coupling reaction of imidazoles and pyrazoles with bromoacetylenes has efficiently been carried out under ligand-free conditions in the presence of copper(II) oxide as the catalyst using potassium hydroxide in 1,4-dioxane at 80 degrees C. The method is a simpler access to N-alk-1-ynyl- and/or N-(2-bromovinyl)-substituted heteroarenes.

引用

页码：816 / 820

页数：5

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