Role of actin filament network in Burkholderia multivorans invasion in well-differentiated human airway epithelia

被引:11
|
作者
Schwab, UE
Ribeiro, CMP
Neubauer, H
Boucher, RC
机构
[1] Univ N Carolina, Cyst Fibrosis Pulm Res & Treatment Ctr, Chapel Hill, NC 27599 USA
[2] FAF Med Acad, Inst Microbiol, Munich, Germany
关键词
D O I
10.1128/IAI.71.11.6607-6609.2003
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The role of the actin-based cytoskeleton in the internalization process of Burkholderia multivorans by well-differentiated human airway epithelia was investigated by immunohistology and confocal microscopy. Our data suggest that an intact actin cytoskeleton is required for biofilm formation but not single cell entry or paracytosis.
引用
收藏
页码:6607 / 6609
页数:3
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