The demographic shift of the worldwide population has already a heavy impact. An ageing population implies increasing necessary resources for health and social systems due to the degenerative diseases, co-morbidities and continuous loss of independence that leads to their institutionalization. In order to avoid as much as possible a dramatic change in seniors' way of living, providing in the same time all the means, supports and facilities to help them to have an active, independent and healthy ageing, multi-disciplinary, age-friendly tools must be developed. The emerging digital technology, the empowerment of the patients regarding the management of their own health, the huge openness and access to health information have already an important social impact. Health informatics, smart devices and IoT-based technologies are increasingly involved in the healthcare of seniors providing thema large range of health supporting services like patient identification, real-time monitoring of vital signals, tracking, location, or personal security. This paper highlights the main approaches for further deploy a health informatics system in order to provide a better support to seniors to live at home and to have real-time access to healthcare services. The proposed software application for the management of senior patients is an update with new components of the PROlonging ACTIVE life for an independent and healthy AGEING (ProActive Ageing) integrated platform for online services. The resulting system will be an on-line monitoring and intelligent decision support system with real-time locating facilities. The system is implemented in collaboration with Romanian health specialists.