Isatuximab plus pomalidomide and dexamethasone in frail patients with relapsed/refractory multiple myeloma: ICARIA-MM subgroup analysis

被引：18

作者：

Schjesvold, Fredrik ^{[1
,2
]}

Bringhen, Sara ^{[3
]}

G. Richardson, Paul ^{[4
]}

Perrot, Aurore ^{[5
]}

Leleu, Xavier ^{[6
,7
]}

Moreau, Philippe ^{[8
]}

A. Dimopoulos, Meletios ^{[9
]}

Hulin, Cyrille ^{[10
]}

Tekle, Christina ^{[11
]}

Foster, Meredith C. ^{[12
]}

Poole, Elizabeth M. ^{[12
]}

van de Velde, Helgi ^{[11
]}

Facon, Thierry ^{[13
]}

机构：

[1] Univ Oslo, Oslo Myeloma Ctr, Dept Haematol, Oslo Univ Hosp, Oslo, Norway

[2] Univ Oslo, KG Jebsen Ctr B Cell Malignancies, Oslo, Norway

[3] Univ Torino, Azienda Osped Univ Citta Salute & Sci Torino, Div Hematol, Myeloma Unit, Turin, Italy

[4] Dana Farber Canc Inst, Boston, MA 02115 USA

[5] Univ Toulouse, UPS, Serv Hematol, CHU Toulouse,IUCT O, Toulouse, France

[6] CHU, Serv Hematol & Therapie Cellulaire, F-1402 Poitiers, France

[7] CIC Inserm, F-1402 Poitiers, France

[8] Univ Nantes, Nantes, France

[9] Natl & Kapodistrian Univ Athens, Sch Med, Dept Clin Therapeut, Athens, Greece

[10] Hop Haut Leveque CHU, Bordeaux, France

[11] Sanofi Oncol, Cambridge, MA USA

[12] Global Med Affairs, Sanofi Genzyme, Cambridge, MA USA

[13] Hopital Claude Huriez, Lille, France

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 2021年 / 96卷 / 11期

关键词：

D O I：

10.1002/ajh.26319

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：E423 / E427

页数：5

共 8 条

[1] Defining the vulnerable patient with myeloma-a frailty position paper of the European Myeloma Network [J].

Cook, Gordon ;

Larocca, Alessandra ;

Facon, Thierry ;

Zweegman, Sonja ;

Engelhardt, Monika .

LEUKEMIA, 2020, 34 (09) :2285-2294

[2] Efficacy and safety of carfilzomib-based regimens in frail patients with relapsed and/or refractory multiple myeloma [J].

Facon, Thierry ;

Niesvizky, Ruben ;

Mateos, Maria-Victoria ;

Siegel, David ;

Rosenbaum, Cara ;

Bringhen, Sara ;

Weisel, Katja ;

Ho, P. Joy ;

Ludwig, Heinz ;

Kumar, Shaji ;

Wang, Kenneth ;

Obreja, Mihaela ;

Yang, Zhao ;

Klippel, Zandra ;

Mezzi, Khalid ;

Goldrick, Amanda ;

Tekle, Christina ;

Dimopoulos, Meletios A. .

BLOOD ADVANCES, 2020, 4 (21) :5449-5459

[3] A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial [J].

Facon, Thierry ;

Dimopoulos, Meletios A. ;

Meuleman, Nathalie ;

Belch, Andrew ;

Mohty, Mohamad ;

Chen, Wen-Ming ;

Kim, Kihyun ;

Zamagni, Elena ;

Rodriguez-Otero, Paula ;

Renwick, William ;

Rose, Christian ;

Tempescul, Adrian ;

Boyle, Eileen ;

Manier, Salomon ;

Attal, Michel ;

Moreau, Philippe ;

Macro, Margaret ;

Leleu, Xavier ;

Chretien, Marie Lorraine ;

Ludwig, Heinz ;

Guo, Shien ;

Sturniolo, Michael ;

Tinel, Antoine ;

Monzini, Mara Silvia ;

Costa, Bruno ;

Houck, Vanessa ;

Hulin, Cyrille ;

Mary, Jean Yves .

LEUKEMIA, 2020, 34 (01) :224-233

[4] Clinical impact of frailty on treatment outcomes of elderly patients with relapsed and/or refractory multiple myeloma treated with lenalidomide plus dexamethasone [J].

Lee, Ho Sup ;

Kim, Kihyun ;

Lee, Je-Jung ;

Yoon, Sung-Soo ;

Bang, Soo-Mee ;

Kim, Jin Seok ;

Eom, Hyeon-Seok ;

Yoon, Dok Hyun ;

Lee, Yoojin ;

Shin, Ho-Jin ;

Park, Yong ;

Jo, Jae-Cheol ;

Lee, Won Sik ;

Do, Young Rok ;

Mun, Yeung-Chul ;

Lee, Mark Hong ;

Kim, Hyo Jung ;

Kim, Sung-Hyun ;

Kim, Min Kyoung ;

Lim, Sung-Nam ;

Park, Seong Kyu ;

Yi, Jun Ho ;

Lee, Jae Hoon ;

Min, Chang-Ki .

INTERNATIONAL JOURNAL OF HEMATOLOGY, 2021, 113 (01) :81-91

[5] External validation of the FIRST trial's simplified frailty score in a population-based cohort [J].

Mian, Hira S. ;

Giri, Smith ;

Wildes, Tanya M. ;

Balitsky, Amaris K. ;

McCurdy, Arleigh ;

Pond, Gregory R. ;

Sivapathasundaram, Branavan ;

Seow, Hsien .

LEUKEMIA, 2021, 35 (06) :1823-1827

[6] Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study [J].

Moreau, Philippe ;

Attal, Michel ;

Hulin, Cyrille ;

Arnulf, Bertrand ;

Belhadj, Karim ;

Benboubker, Lotfi ;

Bene, Marie C. ;

Broijl, Annemiek ;

Caillon, Helene ;

Caillot, Denis ;

Corre, Jill ;

Delforge, Michel ;

Dejoie, Thomas ;

Doyen, Chantal ;

Facon, Thierry ;

Sonntag, Cecile ;

Fontan, Jean ;

Garderet, Laurent ;

Jie, Kon-Siong ;

Karlin, Lionel ;

Kuhnowski, Frederique ;

Lambert, Jerome ;

Leleu, Xavier ;

Lenain, Pascal ;

Macro, Margaret ;

Mathiot, Claire ;

Orsini-Piocelle, Frederique ;

Perrot, Aurore ;

Stoppa, Anne-Marie ;

van de Donk, Niels W. C. J. ;

Wuilleme, Soraya ;

Zweegman, Sonja ;

Kolb, Brigitte ;

Touzeau, Cyrille ;

Roussel, Murielle ;

Tiab, Mourad ;

Marolleau, Jean-Pierre ;

Meuleman, Nathalie ;

Vekemans, Marie-Christiane ;

Westerman, Matthijs ;

Klein, Saskia K. ;

Levin, Mark-David ;

Fermand, Jean Paul ;

Escoffre-Barbe, Martine ;

Eveillard, Jean-Richard ;

Garidi, Reda ;

Ahmadi, Tahamtan ;

Zhuang, Sen ;

Chiu, Christopher ;

Pei, Lixia .

LANCET, 2019, 394 (10192) :29-38

[7] Geriatric assessment predicts survival and toxicities in elderly myeloma patients: an International Myeloma Working Group report [J].

Palumbo, Antonio ;

Bringhen, Sara ;

Mateos, Maria-Victoria ;

Larocca, Alessandra ;

Facon, Thierry ;

Kumar, Shaji K. ;

Offidani, Massimo ;

McCarthy, Philip ;

Evangelista, Andrea ;

Lonial, Sagar ;

Zweegman, Sonja ;

Musto, Pellegrino ;

Terpos, Evangelos ;

Belch, Andrew ;

Hajek, Roman ;

Ludwig, Heinz ;

Stewart, A. Keith ;

Moreau, Philippe ;

Anderson, Kenneth ;

Einsele, Hermann ;

Durie, Brian G. M. ;

Dimopoulos, Meletios A. ;

Landgren, Ola ;

San Miguel, Jesus F. ;

Richardson, Paul ;

Sonneveld, Pieter ;

Rajkumar, S. Vincent .

BLOOD, 2015, 125 (13) :2068-2074

[8] Isatuximab plus pomalidomide and dexamethasone in elderly patients with relapsed/refractory multiple myeloma: ICARIA-MM subgroup analysis [J].

Schjesvold, Fredrik ;

Richardson, Paul G. ;

Facon, Thierry ;

Alegre, Adrian ;

Spencer, Andrew ;

Jurczyszyn, Artur ;

Sunami, Kazutaka ;

Frenzel, Laurent ;

Min, Chang-Ki ;

Guillonneau, Sophie ;

Lin, Peggy L. ;

Le-Guennec, Solenn ;

Campana, Frank ;

van de Velde, Helgi ;

Bensfia, Samira ;

Bringhen, Sara .

HAEMATOLOGICA, 2021, 106 (04) :1182-1187

← 1 →