Chemokine and cytokine processing by matrix metalloproteinases and its effect on leukocyte migration and inflammation

被引：442
作者：
Van Lint, Philippe
Libert, Claude
机构：
[1] Univ Ghent VIB, Dept Mol Biomed Res, Ghent, Belgium
[2] Univ Ghent VIB, Dept Mol Biol, Ghent, Belgium
来源：
JOURNAL OF LEUKOCYTE BIOLOGY | 2007年 / 82卷 / 06期
关键词：
extracellular matrix; ELR; NECROSIS-FACTOR-ALPHA; GROWTH-FACTOR-BETA; HERNIATED DISC RESORPTION; ACUTE LUNG INJURY; GELATINASE-B; AIRWAY INFLAMMATION; TGF-BETA; EXTRACELLULAR-MATRIX; CHEMOTACTIC ACTIVITY; MACROPHAGE ELASTASE;
D O I：
10.1189/jlb.0607338
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The action of matrix metalloproteinases (MMPs) was originally believed to be restricted to degradation of the extracellular matrix; however, in recent years, it has become evident that these proteases can modify many nonmatrix substrates, such as cytokines and chemokines. The use of MMP-deficient animals has revealed that these proteases can indeed influence the progression of various inflammatory processes. This review aims to provide the reader with a concise overview of these novel MMP functions in relation to leukocyte migration.
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收藏
页码：1375 / 1381
页数：7
相关论文
共 75 条
[1]   A site on laminin α5, AQARSAASKVKVSMKF, induces inflammatory cell production of matrix metalloproteinase-9 and chemotaxis [J].
Adair-Kirk, TL ;
Atkinson, JJ ;
Broekelmann, TJ ;
Doi, M ;
Tryggvason, K ;
Miner, JH ;
Mecham, RP ;
Senior, RM .
JOURNAL OF IMMUNOLOGY, 2003, 171 (01) :398-406
[2]   Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis [J].
Agrawal, S ;
Anderson, P ;
Durbeej, M ;
van Rooijen, N ;
Ivars, F ;
Opdenakker, G ;
Sorokin, LM .
JOURNAL OF EXPERIMENTAL MEDICINE, 2006, 203 (04) :1007-1019
[3]   Loss of collagenase-2 confers increased skin tumor susceptibility to male mice [J].
Balbín, M ;
Fueyo, A ;
Tester, AM ;
Pendás, AM ;
Pitiot, AS ;
Astudillo, A ;
Overall, CM ;
Shapiro, SD ;
López-Otín, C .
NATURE GENETICS, 2003, 35 (03) :252-257
[4]  
BANDA MJ, 1988, J BIOL CHEM, V263, P4481
[5]   Increased soluble interleukin-1 receptor type II proteolysis in the endometrium of women with endometriosis [J].
Bellehumeur, C ;
Collette, T ;
Maheux, R ;
Mailloux, J ;
Villeneuve, M ;
Akoum, A .
HUMAN REPRODUCTION, 2005, 20 (05) :1177-1184
[6]   The shedding of syndecan-4 and syndecan-1 from HeLa cells and human primary macrophages is accelerated by SDF-1/CXCL12 and mediated by the matrix metalloproteinase-9 [J].
Brule, Severine ;
Charnaux, Nathalie ;
Sutton, Angela ;
Ledoux, Dominique ;
Chaigneau, Thomas ;
Saffar, Line ;
Gattegno, Liliane .
GLYCOBIOLOGY, 2006, 16 (06) :488-501
[7]   Matrix metalloproteinase-9 deficiency impairs cellular infiltration and bronchial hyperresponsiveness during allergen-induced airway inflammation [J].
Cataldo, DD ;
Tournoy, KG ;
Vermaelen, K ;
Munaut, C ;
Foidart, JM ;
Louis, R ;
Noël, A ;
Pauwels, RA .
AMERICAN JOURNAL OF PATHOLOGY, 2002, 161 (02) :491-498
[8]  
CLARK RAF, 1988, J BIOL CHEM, V263, P12115
[9]   MMP-2 is required for bone marrow stromal cell support of pro-B-cell chemotaxis [J].
Clutter, SD ;
Fortney, J ;
Gibson, LF .
EXPERIMENTAL HEMATOLOGY, 2005, 33 (10) :1192-1200
[10]   Overlapping and independent contributions of MMP2 and MMP9 to lung allergic inflammatory cell egression through decreased CC chemokines [J].
Corry, DB ;
Kiss, A ;
Song, LZ ;
Song, L ;
Xu, J ;
Lee, SH ;
Werb, Z ;
Kheradmand, F .
FASEB JOURNAL, 2004, 18 (06) :995-+
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