Development of Taenia saginata asiatica metacestodes in SCID mice and its infectivity in human and alternative definitive hosts

被引：7

作者：

Chang, SL

Nonaka, N

Kamiya, M

Kanai, Y

Ooi, HK

Chung, WC

Oku, Y ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Vet Med, Parasitol Lab, Sapporo, Hokkaido 0600818, Japan

[2] Rakuno Gakuen Univ, Fac Environm Syst, Dept Biosphere & Environm Sci, Lab Environm Zool, Ebetsu, Hokkaido 0698501, Japan

[3] Natl Chung Hsing Univ, Dept Vet Med, Taipei, Taiwan

[4] Taipei Med Univ, Dept Parasitol, Taipei, Taiwan

来源：

PARASITOLOGY RESEARCH | 2005年 / 96卷 / 02期

基金：

日本学术振兴会;

关键词：

D O I：

10.1007/s00436-005-1328-4

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Development of Taenia saginata asiatica metacestodes in SCID mice, and its infectivity in humans, golden hamsters, and Mongolian gerbils as alternative definitive hosts, were investigated. Cysticerci were recovered from SCID mice that were subcutaneously injected with hatched oncospheres of T. s. asiatica. The morphological changes of metacestodes were observed. The recovered cysticerci were fed to gerbils, hamsters and humans, to check for their infectivity. Tapeworms were recovered from gerbils and hamsters fed with 20 to 45 week-old cysticerci, and proglottids excretions were observed in human volunteers fed with 45 week-old cysticerci. However, no tapeworms were recovered from gerbils fed with 10 week-old cysticerci. Our results suggest that T. s. asiatica oncospheres needed more than 20 weeks to develop to maturity in SCID mice to be infective to both their natural and alternative definitive hosts.

引用

页码：95 / 101

页数：7

共 37 条

[11]

FAN P-C, 1990, Yonsei Reports on Tropical Medicine, V21, P39

[12] EXPERIMENTAL-INFECTION OF THAILAND TAENIA (CHIENGMAI STRAIN) IN DOMESTIC-ANIMALS [J].