Effect of a low-dielectric interior on DNA electrostatic response to twisting and bending

被引：19

作者：

Cherstvy, A. G.

机构：

[1] Max Planck Inst Phys Komplexer Syst, D-01187 Dresden, Germany

[2] Forschungszentrum Julich, Inst Festkorperforsch, D-52425 Julich, Germany

来源：

JOURNAL OF PHYSICAL CHEMISTRY B | 2007年 / 111卷 / 44期

关键词：

D O I：

10.1021/jp074166z

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We study the effects of a low-dielectric core of rod-like macromolecules on their electrostatic persistence lengths. We use the exact solution of the linear Poisson-Boltzmann equation for the potential of a charge on the surface of a low-dielectric cylinder. We apply the results to the B-DNA molecule, modeled as a double helical array of discrete charges wound on the surface of a low-dielectric rod. For this charge geometry, we calculate the change in the electrostatic twist persistence as compared to DNA with a water-permeable core. We also discuss possible effects of the low-dielectric molecular core on DNA bending persistence.

引用

收藏

页码：12933 / 12937

页数：5

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