The Significance of Non-T-Cell Pathways in Graft Rejection: Implications for Transplant Tolerance

被引：23
作者：
Li, Xian Chang [1 ,2 ]
机构：
[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Dept Med,Transplant Inst, Boston, MA 02215 USA
[2] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Dept Surg,Transplant Inst, Boston, MA 02215 USA
来源：
TRANSPLANTATION | 2010年 / 90卷 / 10期
基金：
美国国家卫生研究院;
关键词：
Innate immunity; NK cells; Dendritic cells; Tolerance; Transplantation; NATURAL-KILLER-CELLS; DENDRITIC CELLS; NK CELLS; B-CELLS; ALLOGRAFT VASCULOPATHY; REGULATORY CELLS; MEMORY; INTERLEUKIN-15; REQUIREMENT; ACTIVATION;
D O I：
10.1097/TP.0b013e3181efcfe9
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Both innate and adaptive immune cells are actively involved in the initiation and destruction of allotransplants, and there is a true need now to look beyond T cells in the allograft response, examining various non-T-cell types in transplant models and how such cell types interact with T cells in determining the fate of an allograft. Studies in this area may lead to further improvement in transplant outcomes.
引用
收藏
页码：1043 / 1047
页数：5
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