Electrochemical oxidation of hyperforin on glassy carbon electrode and determination in herbal medicinal products

被引:2
作者
Michelitsch, A [1 ]
Wurglics, M
机构
[1] Karl Franzens Univ Graz, Inst Pharmaceut Chem & Pharmaceut Technol, Graz, Austria
[2] Univ Frankfurt, Inst Pharmaceut Chem, D-6000 Frankfurt, Germany
关键词
hyperforin; differential pulse voltammetry; cyclic voltammetry; glassy carbon electrode; herbal medicinal products;
D O I
10.1002/elan.200390098
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Hyperfolin, one of the active components of St. John's Wort and St. John's Wort extracts is oxidized on the glassy carbon electrode. Electrode process, type and reversibility were examined by means of cyclic voltammetry in various buffer systems (NaAc/HAc, Sorensen-phosphate buffer, borate buffer). A differential pulse voltammetric method was developed for the determination of hyperforin. In the concentration range from 1.0 wg/mL to 40.0 mug/mL there is a strong linearity between the concentration of hyperforin and peak height. The detection limit is 200 ng/mL. The differential pulse voltammetric method developed is used to determine hyperforin in herbal medicinal products.
引用
收藏
页码:797 / 802
页数:6
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