Consumption of herbal remedies and dietary supplements amongst patients hospitalized in medical wards

被引:55
|
作者
Goldstein, Lee H. [1 ]
Elias, Mazen
Ron-Avraham, Gilat
Biniaurishvili, Ben Zion
Madjar, Magali
Kamargash, Irena
Braunstein, Rony
Berkovitch, Matitiahu
Golik, Ahuva
机构
[1] Assaf Harofeh Med Ctr, Clin Pharmacol & Toxicol Unit, IL-70300 Zerifin, Israel
[2] Assaf Harofeh Med Ctr, Internal Dept A, IL-70300 Zerifin, Israel
[3] Tel Aviv Univ, Affiliated Sackler Sch Med, IL-69978 Tel Aviv, Israel
[4] Haemek Med Ctr, Internal Med Dept C, Afula, Israel
[5] Affiliated Bruce Rappaport Sch Med, Haifa, Israel
[6] Hadassah hebrew Univ, Med Ctr, Ctr Qual & Safety, Jerusalem, Israel
关键词
dietary supplements; drug interactions; herbal medicine; herb-drug interactions; inpatients; internal medicine;
D O I
10.1111/j.1365-2125.2007.02878.x
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Aims Herbal remedies may have adverse effects and potentially serious interactions with some commonly prescribed conventional medications. Little is known about consumption of herbal remedies and dietary supplements by hospitalized patients. The aim was to evaluate the rate of consumption and characterize the patients hospitalized in internal medicine departments who consume herbal remedies and dietary supplements. Also, to assess the medical teams' awareness and assess the percentage of patients with possible drug-herb interactions. Methods Patients hospitalized in the medical wards of two hospitals in Israel were interviewed about their use of herbal remedies or dietary supplements. The medical records were searched for evidence that the medical team had knowledge of the use of herbal remedies or dietary supplements. Results Two hundred and ninety-nine hospitalized medical patients were interviewed. Of the participants, 26.8% were herbal or dietary supplement consumers (HC). On multivariate analysis the only variates associated with herbal or dietary supplement consumption were the hospital [odds ratio (OR) 2.97, 95% confidence interval (CI) 1.29, 6.52], income (OR 0.39, 95% CI 0.15, 1.05), smoking habits (OR 0.17, 95% CI 0.05, 0.55) and benign prostatic hypertrophy (OR 4.64, 95% CI 1.3, 16.5). Ninety-four percent of the patients had not been asked specifically of herbal consumption by the medical team. Only 23% of the hospital's medical files of the HC patients had any record of the use of herbal or dietary supplements. Seven possible drug-herbal interactions were encountered (7.1%). The most serious was an interaction between camomile tea and ciclosporin. Conclusions Herbal remedy consumption is common amongst patients hospitalized in internal medicine wards and is often overlooked by the medical team. Patients and doctors should be more aware of the possible adverse effects and of the potential of herb-drug interactions.
引用
收藏
页码:373 / 380
页数:8
相关论文
共 50 条
  • [1] Consumption of herbal remedies and dietary supplements amongst patients hospitalized in medical wards.
    Goldstein, L. H.
    Elias, M.
    Ron-Avraham, G.
    Biniaurishvili, B.
    Madjar, M.
    Kamargash, I.
    Braunstein, R.
    Berkovitch, M.
    Golik, A.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2007, 81 : S29 - S29
  • [2] Herbal remedies, dietary supplements, and seizures
    Tyagi, A
    Delanty, N
    EPILEPSIA, 2003, 44 (02) : 228 - 235
  • [3] Are herbal remedies and dietary supplements safe and effective for breast cancer patients?
    Cassidy, A
    BREAST CANCER RESEARCH, 2003, 5 (06) : 300 - 302
  • [4] Are herbal remedies and dietary supplements safe and effective for breast cancer patients?
    Aedin Cassidy
    Breast Cancer Research, 5
  • [5] Dietary and herbal supplements use among patients hospitalized in internal medicine departments
    Ben-Sasson, M.
    Levy, I
    Ben-Arye, E.
    Attias, S.
    Schiff, E.
    COMPLEMENTARY THERAPIES IN MEDICINE, 2020, 50
  • [6] Determination of Oxalate Content in Herbal Remedies and Dietary Supplements Based on Plant Extracts
    Siener, Roswitha
    Lopez-Mesas, Montserrat
    Valiente, Manuel
    Blanco, Francisco
    JOURNAL OF MEDICINAL FOOD, 2016, 19 (02) : 205 - 210
  • [7] Interactions between dietary supplements in hospitalized patients
    Ilana Levy
    Samuel Attias
    Eran Ben Arye
    Lee Goldstein
    Elad Schiff
    Internal and Emergency Medicine, 2016, 11 : 917 - 927
  • [8] Interactions between dietary supplements in hospitalized patients
    Muscaritoli, Maurizio
    INTERNAL AND EMERGENCY MEDICINE, 2016, 11 (07) : 903 - 904
  • [9] Interactions between dietary supplements in hospitalized patients
    Maurizio Muscaritoli
    Internal and Emergency Medicine, 2016, 11 : 903 - 904
  • [10] Use of dietary and herbal supplements in adult patients with epilepsy
    Bosa, Magdalena
    Molek, Patrycja
    Slowik, Agnieszka
    EPILEPSY RESEARCH, 2019, 156