Dearomative oxyphosphorylation of indoles enables facile access to 2,2-disubstituted indolin-3-ones

被引：4
|
作者：
Xiong, Ting [1 ]
Zhou, Xingcui [1 ]
Jiang, Jun [1 ]
机构：
[1] Guangxi Univ, Sch Chem & Chem Engn, Guangxi Key Lab Electrochem Energy Mat, Nanning 530004, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2022年 / 20卷 / 29期
基金：
中国国家自然科学基金;
关键词：
OXIDATIVE DEAROMATIZATION; 2-ALKYNYL ARYLAZIDES; AEROBIC OXYGENATION; REDOX ANNULATION; ROUTE; CONSTRUCTION; NITROALKYNES; ARYLATION; TRANSFORMATION; PSEUDOINDOXYL;
D O I：
10.1039/d2ob01063a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly efficient oxidative dearomatization of indoles with H-phosphorus oxides in the presence of TEMPO oxoammonium salt has been demonstrated. Through the intramolecular oxidative dearomatization of indoles and subsequent intermolecular nucleophilic addition with phosphorus nucleophile, a variety of structurally diverse arylphosphoryl and alkylphosphoryl indolin-3-ones were obtained in good yields with a broad substrate scope and high functional-group compatibility.
引用
收藏
页码：5721 / 5725
页数：5
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