In vitro and in vivo activities of sitafloxacin against Chlamydia spp.

被引：18
|
作者：
Miyashita, N [1 ]
Niki, Y [1 ]
Matsushima, T [1 ]
机构：
[1] Kawasaki Med Sch, Dept Med, Div Resp Dis, Okayama 7010192, Japan
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 11期
关键词：
D O I：
10.1128/AAC.45.11.3270-3272.2001
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The in vitro and in vivo antichlamydial activity of sitafloxacin was investigated. The MICs and minimal chlamydiacidal concentrations of sitafloxacin for various species of chlamydia ranged from 0.031 to 0.125 mug/ml. Sitafloxacin had an excellent therapeutic effect on experimental Chlamydia psittaci pneumonia and was more potent than tosufloxacin, ofloxacin, and ciproflxacin, although slightly less potent than sparfloxacin.
引用
收藏
页码：3270 / 3272
页数：3
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