Targeting of motor proteins

被引：257

作者：

Vallee, RB ^{[1
]}

Sheetz, MP ^{[1
]}

机构：

[1] DUKE UNIV,DEPT CELL BIOL,DURHAM,NC 27710

来源：

SCIENCE | 1996年 / 271卷 / 5255期

关键词：

D O I：

10.1126/science.271.5255.1539

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Microtubules are responsible for chromosome segregation and the movement and reorganization of membranous organelles. Many aspects of microtubule-based motility can be attributed to the action of motor proteins, producing force directed toward either end of microtubules. How these proteins are targeted to the appropriate organellar sites within the cell, however, has remained a mystery. Recent work has begun to define the targeting mechanism for two well-studied motor proteins, kinesin and cytoplasmic dynein.

引用

页码：1539 / 1544

页数：6

共 122 条

[11]

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