Wild birds as a possible natural reservoir of Borna disease virus

被引:50
作者
Berg, M
Johansson, M
Montell, H
Berg, AL [1 ]
机构
[1] AstraZeneca, R&D Sodertaije, Safety Assessment, S-15185 Sodertalje, Sweden
[2] Uppsala Grad Sch Biomed Res, Uppsala, Sweden
[3] Swedish Univ Agr Sci, Dept Pathol, Uppsala, Sweden
[4] Swedish Univ Agr Sci, Dept Vet Microbiol, Immunol Sect, Uppsala, Sweden
关键词
D O I
10.1017/S0950268801005702
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The natural reservoir of Borna disease virus (BDV) is unknown. In this paper, we show that mallards (Anas platyrhyncos) and jackdaws (Corvus monedula) can be subclinically infected carriers of this virus. From faecal samples collected at a bird pond, we were able to amplify fragments of the BDV p24 and p40 genes. Following cloning and sequencing, a phylogenetic analysis revealed that these birds carry strains of BDV closely related to but distinct from the reference strains BDV V and He/80, To our knowledge, this is the first confirmed finding of BDV in wild birds.
引用
收藏
页码:173 / 178
页数:6
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