Synthesis and structure determination of some oxadiazole-2-thione and triazole-3-thione galactosides

被引：32

作者：

Ahmad, R ^{[1
]}

Iqbal, R

Akhtar, H

Zia-ul-Haq

Duddeck, H

Stefaniak, L

Sitkowski, J

机构：

[1] Quaid I Azam Univ, Dept Chem, Islamabad, Pakistan

[2] Univ Hannover, Inst Organ Chem, D-30167 Hannover, Germany

[3] Polish Acad Sci, Inst Organ Chem, PL-01224 Warsaw, Poland

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2001年 / 20卷 / 09期

关键词：

D O I：

10.1081/NCN-100105903

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The syntheses of 5-pyridyl-3(beta -D-galactopyranosyl)-1,3,4-oxadiazole-2-thiones 3a-3c and 5-pyridyl-2(beta -D-galactopyranosyl)-4-benzyl-1,2, 4-triazole-3-thiones 6a-6c are reported. The existence of N-galactosides - not S-galactosides - was proven by IR and N-15 NMR spectroscopy. The structures of the final products and the intermediates were elucidated by IR, H-1, C-13 and N-15 NMR spectroscopy and mass spectrometry.

引用

页码：1671 / 1682

页数：12

共 20 条

[1] PREPARATION AND REACTIONS OF GLUCOSIDES .2. PREPARATION AND SOME REACTIONS OF D-GLUCOSYL DERIVATIVES OF 2-THIOXO-1,3,4-OXADIAZOLES AND 2-THIOXO-1,3,4-THIADIAZOLES AND THEIR 2-OXO ANALOGS [J].