Synthesis and structure determination of some oxadiazole-2-thione and triazole-3-thione galactosides

被引:32
作者
Ahmad, R [1 ]
Iqbal, R
Akhtar, H
Zia-ul-Haq
Duddeck, H
Stefaniak, L
Sitkowski, J
机构
[1] Quaid I Azam Univ, Dept Chem, Islamabad, Pakistan
[2] Univ Hannover, Inst Organ Chem, D-30167 Hannover, Germany
[3] Polish Acad Sci, Inst Organ Chem, PL-01224 Warsaw, Poland
关键词
D O I
10.1081/NCN-100105903
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The syntheses of 5-pyridyl-3(beta -D-galactopyranosyl)-1,3,4-oxadiazole-2-thiones 3a-3c and 5-pyridyl-2(beta -D-galactopyranosyl)-4-benzyl-1,2, 4-triazole-3-thiones 6a-6c are reported. The existence of N-galactosides - not S-galactosides - was proven by IR and N-15 NMR spectroscopy. The structures of the final products and the intermediates were elucidated by IR, H-1, C-13 and N-15 NMR spectroscopy and mass spectrometry.
引用
收藏
页码:1671 / 1682
页数:12
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