Phenolic Glucosides from the Leaves of Vitex negundo var. cannabifolia

被引：0

作者：

Sun, Jing ^{[1
,2
]}

Li, Manman ^{[1
]}

Wang, Yongru ^{[2
]}

Chang, Chuang ^{[1
]}

Pei, Yujie ^{[1
]}

Zeng, Kewu ^{[3
]}

Zhao, Yunfang ^{[1
]}

Zheng, Jiao ^{[1
]}

Song, Yuelin ^{[1
]}

Tu, Pengfei ^{[1
]}

Huo, Huixia ^{[1
]}

Li, Jun ^{[1
]}

机构：

[1] Beijing Univ Chinese Med, Modern Res Ctr Tradit Chinese Med, Sch Chinese Mat Med, Beijing 100029, Peoples R China

[2] Chinese Acad Agr Sci, Inst Food Sci & Technol, Beijing 100193, Peoples R China

[3] Peking Univ Hlth Sci Ctr, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

来源：

CHEMISTRY & BIODIVERSITY | 2022年 / 19卷 / 11期

基金：

国家重点研发计划;

关键词：

Verbenaceae; Vitex negundo var; cannabifolia; phenolic glucosides; anti-inflammation; CONSTITUENTS;

D O I：

10.1002/cbdv.202200652

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Four new phenolic glucosides, cannabifolins G-J (1-4), together with four known ones (5-8), were isolated from the leaves of Vitex negundo var. cannabifolia. Their structures were established by comprehensive analysis of 1D and 2D NMR data and comparison of their spectroscopic and physical data with the literature values. Compound 7 exhibited weak inhibition of nitric oxide production stimulated by lipopolysaccharide in BV-2 microglial cells with IC50 value of 132.8 mu M.

引用

页数：7

共 50 条

[21] Bioactive constituents from Vitex negundo var. heterophylla and their antioxidant and α-glucosidase inhibitory activities
Hu, Ping
Li, Da-Hong
Jia, Cui-Cui
Liu, Quan
Wang, Xiao-Fei
Li, Zhan-Lin
Hua, Hui-Ming
JOURNAL OF FUNCTIONAL FOODS, 2017, 35 : 236 - 244
[22] Phenolic Glucosides from Dendrobium aurantiacum var. denneanum and Their Bioactivities
Xiong, Liang
Cao, Zhi-Xing
Peng, Cheng
Li, Xiao-Hong
Xie, Xiao-Fang
Zhang, Ting-Mo
Zhou, Qin-Mei
Yang, Lian
Guo, Li
MOLECULES, 2013, 18 (06): : 6153 - 6160
[23] Morphological response of Vitex negundo var. heterophylla and Ziziphus jujuba var. spinosa to the combined impact of drought and shade
Du, Ning
Wang, Renqing
Liu, Jian
Zhang, Xiuru
Tan, Xiangfeng
Wang, Wei
Chen, Hua
Guo, Weihua
AGROFORESTRY SYSTEMS, 2013, 87 (02) : 403 - 416
[24] Morphological response of Vitex negundo var. heterophylla and Ziziphus jujuba var. spinosa to the combined impact of drought and shade
Ning Du
Renqing Wang
Jian Liu
Xiuru Zhang
Xiangfeng Tan
Wei Wang
Hua Chen
Weihua Guo
Agroforestry Systems, 2013, 87 : 403 - 416
[25] Volatile constituents of Vitex negundo leaves
Singh, V
Dayal, R
Bartley, JP
PLANTA MEDICA, 1999, 65 (06) : 580 - 582
[26] Chemical Composition and the Regional Effect of Vitex negundo Linn. var. cannabifolia (Sieb.et Zucc.) Hand.-Mazz. Essential oils and the Regional Effect on it
Tang, Ying
Chen, Gang
Zhang, Jie
Mu, Shu-Zhen
JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN, 2011, 33 (05): : 744 - 746
[27] Development and characterization of EST-SSR markers for Vitex negundo var. heterophylla (Lamiaceae)
Liu, Lele
Wang, Jingwen
Yin, Meiqi
Guo, Xiao
Cai, Yunfei
Du, Ning
Yu, Xiaona
Guo, Weihua
APPLICATIONS IN PLANT SCIENCES, 2019, 7 (01):
[28] Phenolic glycosides from the leaves of Alangium platanifolium var. platanifolium
Tamaki, A
Ide, T
Otsuka, H
JOURNAL OF NATURAL PRODUCTS, 2000, 63 (10): : 1417 - 1419
[29] IRIDOIDS FROM VITEX-CANNABIFOLIA
IWAGAWA, T
NAKAHARA, A
NAKATANI, M
PHYTOCHEMISTRY, 1993, 32 (02) : 453 - 454
[30] The chloroplast genome sequence and characteristic analysis of Vitex negundo var. heterophylla (Franch.) Rehder
Zheng, Guangshun
Li, Jianbo
Diao, Shu
MITOCHONDRIAL DNA PART B-RESOURCES, 2021, 6 (12): : 3508 - 3510

← 1 2 3 4 5 →