Observation of electric-field induced aggregation in crystallizing protein solutions by forward light scattering

被引：10
作者：
Wakamatsu, Takashi [1 ]
Toyoshima, Susumu [2 ]
Shimizu, Hidehiko [3 ]
机构：
[1] Ibaraki Natl Coll Technol, Dept Elect & Elect Syst Engn, Hitachinaka, Ibaraki 3128508, Japan
[2] Fukushima Natl Coll Technol, Dept Elect Engn, Fukushima 9708034, Japan
[3] Niigata Univ, Dept Elect & Elect Engn, Niigata 9502181, Japan
来源：
APPLIED PHYSICS LETTERS | 2011年 / 99卷 / 15期
基金：
日本科学技术振兴机构;
关键词：
MAGNETIC-FIELD; LYSOZYME CRYSTALS; NUCLEATION; GROWTH;
D O I：
10.1063/1.3648114
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
Protein aggregation has been observed in-situ in lysozyme solutions under an internal electric field using a forward light scattering technique. Light scattering at small forward angles revealed that the application of a low voltage to the protein solutions significantly promotes aggregate formation. The solutions required a specific amount of time exposed to an electric field before the solution had undergone sufficient protein aggregation. The in-situ results from forward light scattering allow the characterization of the process. (C) 2011 American Institute of Physics. [doi:10.1063/1.3648114]
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页数：3
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