3-azabicyclo[3.3.1]nonane derivatives: IV. Synthesis of amino acids with 3-azabicyclo[3.3.1]nonane fragment

被引：2
|
作者：
Shakhkel'dyan, IV [1 ]
Nikiforova, EG
Grudtsyn, YD
Atroshchenko, YM
Borbulevich, OY
Efremov, YA
Gitis, SS
Moiseev, DN
Alifanova, EN
Chudakov, PV
Kovalevskii, AY
机构：
[1] Lev Tolstoi Tula State Pedag Univ, Tula 300600, Russia
[2] Russian Acad Sci, Nesmeyanov Inst Organoelemental Cpds, Moscow, Russia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 37卷 / 04期
基金：
俄罗斯基础研究基金会;
关键词：
Acetic; Potassium; Formaldehyde; Acetic Acid; Organic Chemistry;
D O I：
10.1023/A:1012402523702
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of 1.5-dinitro-3-azabicyclo[3.3.1]non-6-enes was prepared by reduction of 1-R-2,4- and 1-R-3,5-dinitrobenzenes with potassium borohydride followed by Mannich reaction with formaldehyde and amino acids. The molecular structure of (6-bromo-1,5-dinitro-3-azabicyclo[3.3.1]non-6-en-3-yl)acetic acid was studied by X-ray diffraction analysis. The mechanism of decomposition under electron impact was determined for (7-methoxy-1,5-dinitro-3-azabicyclo[3.3.1]non-6-en-3-yl)acetic acid.
引用
收藏
页码：583 / 591
页数：9
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