The Antibiotic Resistance Profiles of Bacterial Strains Isolated from Patients who had Gram-negative Bacterial Infections

This was a cross-sectional study carried out in a general hospital in Riyadh Region to describe the antibiotic resistance profiles of bacterial strains isolated from patients who had Gram-negative bacterial infections. More than 79% of the bacterial isolates were Gram-negative bacteria isolates. The most common Gram-negative bacteria were Escherichia coli (28.70%), Klebsiella pneumoniae (23.48%), Pseudomonas aeruginosa (16.52%), and Acinetobacter baumannii (13.33%). The resistance of Escherichia coli to 9 antibiotics was more than 50% and for 7 antibiotics less than 50%. The resistance of Klebsiella pneumoniae was more than 50% to 15 antibiotics and less than 50% only for 1 antibiotic. The resistance of Pseudomonas aeruginosa was more or equal to 50% for only 2 antibiotics and for other antibiotics the resistance was less than 50%. The resistance of Acinetobacter baumannii was very high for all of the tested antibiotics except colistin. It is important to implement antimicrobial stewardship programs and to follow the recommendations of infection control units in order to decrease the spread of these resistant bacteria.