Synthesis, characterization and antimicrobial activity of some 3-(2-(1H-benzo[d]imidazol-2-yl)phenyl)-2-arylthiazolidin-4-ones

被引：0
|
作者：
Desai, N. C. [1 ]
Bhatt, Nayan [1 ]
Kumar, Mukesh [1 ]
Makwana, Atul [1 ]
机构：
[1] Bhavnagar Univ, Univ Dept Chem, Div Med Chem, Bhavnagar 364002, Gujarat, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2011年 / 50卷 / 07期
关键词：
2-Aminobenzoic acid; benzene-1,2-diamine; benzimidazole; thiazolidinone; antibacterial activity; antifungal activity; BIOLOGICAL-ACTIVITY; DERIVATIVES; BENZIMIDAZOLES; METABOLITES; AGENTS; DRUG;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
As a part of systematic investigation of synthesis, characterization and biological activities, several new 3-(2-(1H-benzo[d]imidazol-2-yl)phenyl)-2-arylthiazolidin-4-ones 3a-I, have been synthesized from Schiff bases of benzimidazoles 2a-I, which have been predared by condensation of different aldehydes with 2-(1H-benzo[d]imidazol-2-yl)benzenamine 1. Compound 1 was obtained by the reaction of 2-aminobenzoic acid and benzenc-1,2-diamine. All the synthesized compounds have been evaluated for their antibacterial and antifungal activities against Escherichia coli. Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes, Candida albicans, Asperigillus niger and Asperigillus clavatus.
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收藏
页码：941 / 945
页数：5
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