Synthesis, characterization and antimicrobial activity of some 3-(2-(1H-benzo[d]imidazol-2-yl)phenyl)-2-arylthiazolidin-4-ones

被引：0
|
作者：
Desai, N. C. [1 ]
Bhatt, Nayan [1 ]
Kumar, Mukesh [1 ]
Makwana, Atul [1 ]
机构：
[1] Bhavnagar Univ, Univ Dept Chem, Div Med Chem, Bhavnagar 364002, Gujarat, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2011年 / 50卷 / 07期
关键词：
2-Aminobenzoic acid; benzene-1,2-diamine; benzimidazole; thiazolidinone; antibacterial activity; antifungal activity; BIOLOGICAL-ACTIVITY; DERIVATIVES; BENZIMIDAZOLES; METABOLITES; AGENTS; DRUG;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
As a part of systematic investigation of synthesis, characterization and biological activities, several new 3-(2-(1H-benzo[d]imidazol-2-yl)phenyl)-2-arylthiazolidin-4-ones 3a-I, have been synthesized from Schiff bases of benzimidazoles 2a-I, which have been predared by condensation of different aldehydes with 2-(1H-benzo[d]imidazol-2-yl)benzenamine 1. Compound 1 was obtained by the reaction of 2-aminobenzoic acid and benzenc-1,2-diamine. All the synthesized compounds have been evaluated for their antibacterial and antifungal activities against Escherichia coli. Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes, Candida albicans, Asperigillus niger and Asperigillus clavatus.
引用
收藏
页码：941 / 945
页数：5
相关论文
共 50 条
  • [41] Structural diversity and luminescent properties of coordination complexes obtained from trivalent lanthanide ions with the ligands: tris((1H-benzo[d]imidazol-2-yl)methyl)amine and 2,6-bis(1H-benzo[d] imidazol-2-yl)pyridine
    Cruz-Navarro, Antonio
    Hernandez-Romero, Delia
    Flores-Parra, Angelina
    Rivera, Jose Maria
    Elena Castillo-Blum, Silvia
    Colorado-Peralta, Raul
    COORDINATION CHEMISTRY REVIEWS, 2021, 427
  • [42] Synthesis and nematicidal activity of 2-(1H-benzo[d]imidazol-2-ylmethyl)-4-aryl-1-thia-4-azaspiro[4.5]decan-3-one
    Srinivas, A.
    Nagaraj, A.
    Reddy, Ch Sanjeeva
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2008, 47 (05): : 787 - 791
  • [43] Synthesis, Characterization and Antimicrobial Evaluation of Transition Metal Complexes of Monodentate 2-(Substituted Phenyl)-1H-benzo[d]imidazoles
    Maru, Minaxi S.
    Shah, Manish K.
    CHIANG MAI JOURNAL OF SCIENCE, 2015, 42 (01): : 216 - 227
  • [44] An Efficient Synthesis, Characterization and Antimicrobial Screening of N-substituted 2-(piperidin-4-yl)-2H-benzo[d] [1,2,3] Triazoles
    Pochampalli, Jalapathi
    Mandala, Devender
    Umapathireddy, Nalla
    Rajakomuraiah, Pompu
    LETTERS IN DRUG DESIGN & DISCOVERY, 2012, 9 (05) : 471 - 478
  • [45] Iron(III) complexes of 2-(1H-benzo[d]imidazol-2-yl)phenol and acetate or nitrate as catalysts for epoxidation of olefins with hydrogen peroxide
    Dutta, Amit Kumar
    Samanta, Suvendu
    Dutta, Supriya
    Lucas, C. Robert
    Dawe, Louise N.
    Biswas, Papu
    Adhikary, Bibhutosh
    JOURNAL OF MOLECULAR STRUCTURE, 2016, 1115 : 207 - 213
  • [46] SYNTHESIS OF 2-(SUBSTITUTED PHENYL)-3-[5-(2-OXO-2H-CHROMEN-3-YL)-1,3,4-OXADIAZOL-2-YL]-1,3-THIAZOLIDIN-4-ONES WITH ANTIMICROBIAL ACTIVITY
    Bhat, Mashooq A.
    Al-Omar, Mohammed A.
    Siddiqui, Nadeem
    ACTA POLONIAE PHARMACEUTICA, 2011, 68 (02): : 295 - 299
  • [47] Transition metal complexes of 2-(2-(1H-benzo[d]imidazol-2-yl)hydrazono)propan-1-ol: Synthesis, characterization, crystal structures and anti-tuberculosis assay with docking studies
    Kamat, Vinayak
    Kokare, Dhoolesh
    Naik, Krishna
    Kotian, Avinash
    Naveen, S.
    Dixit, Sheshagiri R.
    Lokanath, N. K.
    Joshi, Shrinivas D.
    Revankar, Vidyanand K.
    POLYHEDRON, 2017, 127 : 225 - 237
  • [48] Synthesis, Single Crystal X-Ray Analysis, Prediction and Study of Pharmacological Activity of 4-(1H-Benzo[d]imidazol-2-yl)-1-Phenyl-1H-1,2,3-triazol-5-Amine and Its Solvates
    Ivachtchenko, Alexandre V.
    Mitkin, Oleg D.
    Kravchenko, Dmitry V.
    Kovalenko, Sergiy M.
    Shishkina, Svitlana V.
    Bunyatyan, Natalya D.
    Konovalova, Irina S.
    Ivanov, Vladimir V.
    Konovalova, Olena D.
    Langer, Thierry
    CRYSTALS, 2019, 9 (12):
  • [49] A Facile Synthesis and Molecular Docking for Anti-inflammatory Activity of 2-(4-Chlorobenzyl)-1-(2-(pyrrolidin-1-yl)ethyl)-1H-benzo[d]imidazol-5-amine and 2-(4-Chlorobenzyl)-1-((1-ethylpyrrolidin-2-yl)methyl)-1H-benzo[d]imidazol-5-amine
    Bucha, Mallaiah
    Eppakayala, Laxminarayana
    Maringanti, Thirumala Chary
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2018, 28 (03) : 321 - 327
  • [50] Preclinical pharmacokinetic characterization of 2-(4-(4-(5-(2-phenyl-5-(trifluoromethyl) oxazole-4-carboxamido)-1H-benzo[d]imidazol-2-yl)phenyl) cyclohexyl) acetic acid, a novel DGAT-1 inhibitor
    Kwak, Eun-Young
    Im, So Hee
    Seo, Hyewon
    Cho, Woon-Ki
    Lee, Ye-Lim
    Woo, Jaechun
    Ahn, Sunjoo
    Ahn, Sung-Hoon
    Kwak, Hyun Jung
    Ahn, Jin Hee
    Bae, Myung Ae
    Song, Jin Sook
    XENOBIOTICA, 2014, 44 (05) : 465 - 471
12345