Synthesis, characterization and antimicrobial activity of some 3-(2-(1H-benzo[d]imidazol-2-yl)phenyl)-2-arylthiazolidin-4-ones

被引：0
|
作者：
Desai, N. C. [1 ]
Bhatt, Nayan [1 ]
Kumar, Mukesh [1 ]
Makwana, Atul [1 ]
机构：
[1] Bhavnagar Univ, Univ Dept Chem, Div Med Chem, Bhavnagar 364002, Gujarat, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2011年 / 50卷 / 07期
关键词：
2-Aminobenzoic acid; benzene-1,2-diamine; benzimidazole; thiazolidinone; antibacterial activity; antifungal activity; BIOLOGICAL-ACTIVITY; DERIVATIVES; BENZIMIDAZOLES; METABOLITES; AGENTS; DRUG;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
As a part of systematic investigation of synthesis, characterization and biological activities, several new 3-(2-(1H-benzo[d]imidazol-2-yl)phenyl)-2-arylthiazolidin-4-ones 3a-I, have been synthesized from Schiff bases of benzimidazoles 2a-I, which have been predared by condensation of different aldehydes with 2-(1H-benzo[d]imidazol-2-yl)benzenamine 1. Compound 1 was obtained by the reaction of 2-aminobenzoic acid and benzenc-1,2-diamine. All the synthesized compounds have been evaluated for their antibacterial and antifungal activities against Escherichia coli. Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes, Candida albicans, Asperigillus niger and Asperigillus clavatus.
引用
收藏
页码：941 / 945
页数：5
相关论文
共 50 条
  • [21] Different synthetic routes to 4-(1H-benzo[d]imidazol-2-yl)aniline
    Muhammad Khattab
    Shadia A. Galal
    Fatma A. F. Ragab
    Hoda I. El Diwani
    Research on Chemical Intermediates, 2013, 39 : 2917 - 2923
  • [22] Different synthetic routes to 4-(1H-benzo[d]imidazol-2-yl)aniline
    Khattab, Muhammad
    Galal, Shadia A.
    Ragab, Fatma A. F.
    El Diwani, Hoda I.
    RESEARCH ON CHEMICAL INTERMEDIATES, 2013, 39 (07) : 2917 - 2923
  • [23] SYNTHESIS OF 1H-BENZO [d] IMIDAZOLO-2-YL-3-ARYL-4-CHLOROCYCLOBUTANONE-2-YL-METHANONES, 1H-BENZO [d] IMIDAZOLO-2-YL-DIHYDRO-5-ARYLTHIOPHEN-3(2H)-ONE-2-YL-METHANONES, 4-(1H-BENZO [d] IMIDAZOL-2-YL)-5,6-DIHYDRO-6-ARYLPYRIMIDINE-2(1H)-THIONES AND 4-(1H)-BENZO [d] IMIDAZOL-2-YL)-5,6-DIHYDRO-6-ARYLPYRIMIDINE-2-(1H)-ONES
    Bhaskar, P.
    Bharahmeswari, G.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2013, 23 (02) : 207 - 212
  • [24] One-Pot Three-Component Synthesis of 3-(1H-Benzo[d]imidazol-2-yl)chromen Derivatives
    Wang, Xiang
    Chen, Ping
    Zhi, Sanjun
    Hu, Huayou
    Kan, Yuhe
    Zhang, Zaichao
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2019, 39 (11) : 3299 - 3303
  • [25] Facile synthesis of substituted benzo[d]pyrrolo[2ʹ,3ʹ:4,5]pyrrolo[1,2-a]imidazoles by 2-(1H-benzo[d]imidazol-2-yl)acetonitrile and arylglyoxals
    Farzaneh Alizadeh-Bami
    Hossein Mehrabi
    Reza Ranjbar-Karimi
    Monatshefte für Chemie - Chemical Monthly, 2022, 153 : 913 - 918
  • [26] Facile synthesis of substituted benzo[d]pyrrolo[2′,3′:4,5] pyrrolo[1,2-a]imidazoles by 2-(1H-benzo[d]imidazol-2-yl)acetonitrile and arylglyoxals
    Alizadeh-Bami, Farzaneh
    Mehrabi, Hossein
    Ranjbar-Karimi, Reza
    MONATSHEFTE FUR CHEMIE, 2022, 153 (10): : 913 - 918
  • [27] In Vitro and InSilico Evaluation of 2-(1H-Benzo[d]imidazol-2-yl)-3-(4-(piperazin-1-yl)phenyl)propanenitrile as Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors
    Sarita, K.
    Kumar, N.
    Agrawal, A.
    Mali, S. N.
    Sharma, S.
    RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2024, 50 (04) : 1563 - 1572
  • [28] Crystal structure of 2-((E)-2-(1H-benzo[d]imidazol-2-yl)vinyl)-1H-benzo[d]imidazolium dichloride dihydrate, C16H18Cl2N4O2
    Schoultz, Xandri
    Gerber, Thomas I. A.
    Hosten, Eric C.
    Betz, Richard
    ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2015, 230 (04): : 315 - 317
  • [29] SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF N-(2-(1-BENZO [d] IMIDAZOL-2-YL)PHENYL)-SUBSTITUTED BENZAMINES
    Singh, Aruna Chandra
    Mittel, Nitin
    Pathak, Devender
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 23 (03) : 225 - 232
  • [30] Three metal(II) complexes constructed using the 2-(1H-benzo[d]imidazol-2-yl)quinoline ligand
    Sahki, Feriel Aouatef
    Bouchouit, Mehdi
    Bouacida, Sofiane
    Messaadia, Lyamine
    Caytan, Elsa
    Chibani, Aissa
    Roisnel, Thierry
    Bouraiou, Abdelmalek
    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2021, 76 (09): : 481 - 487
12345