Early effects of human papillomavirus vaccination in Belgium

被引：11

作者：

Merckx, Mireille ^{[1
,2
]}

Vanden Broeck, Davy ^{[1
]}

Benoy, Ina ^{[3
]}

Depuydt, Christophe ^{[3
]}

Weyers, Steven ^{[2
]}

Arbyn, Marc ^{[4
]}

机构：

[1] Univ Ghent, ICRH, B-9000 Ghent, Belgium

[2] Ghent Univ Hosp, Dept Obstet & Gynaecol, Ghent, Belgium

[3] Son Hlth Care AML, Antwerp, Belgium

[4] Sci Inst Publ Hlth, Canc Epidemiol Unit, Brussels, Belgium

来源：

EUROPEAN JOURNAL OF CANCER PREVENTION | 2015年 / 24卷 / 04期

关键词：

CROSS-PROTECTIVE EFFICACY; GRADE CERVICAL LESIONS; METAANALYSIS; PREVENTION; INFECTION; CANCER;

D O I：

10.1097/CEJ.0000000000000067

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Human papillomavirus (HPV) vaccination has been reimbursed in Belgium since 2007 for girls (12-15 years), extended to girls up to 18 years in 2008. This study assesses the trend of HPV 16/18 infections in women less than 25 years of age participating in opportunistic cervical cancer screening. A significant reduction in the prevalence of HPV 16 [relative risk (RR)=0.61, 95% confidence interval=0.39-0.95] and a nonsignificant reduction in HPV 18 (RR=0.65, 95% confidence interval=0.29-1.48) was found in the youngest group (15-19 years). The prevalences in the older age group did not change significantly. These findings show the early effects of HPV vaccination and confirm the effectiveness of immunization in a real-life setting.

引用

页码：340 / 342

页数：3

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