A facile synthesis of 4-and 6-aryl-substituted steroids by the Suzuki-Miyaura cross-coupling reaction

被引：17

作者：

Lukashev, NV

Latyshev, GV

Donez, PA

Skryabin, GA

Beletskaya, IP

机构：

[1] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119992, Russia

[2] Ambiotech Inc, Baltimore, MD 21202 USA

来源：

SYNTHESIS-STUTTGART | 2005年 / 10期

关键词：

cross-coupling; palladium; steroids; Suzuki reaction; arylation;

D O I：

10.1055/s-2005-865287

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Potential aromatase inhibitors -4- and 6-aryl-SLibstitLited derivatives of androst-4-ene-3.17-dione and 17-hydroxyprogesterone - have been prepared by the Suzuki-Miyaura cross-coupling from their corresponding 4- and 6-bromo steroids.

引用

页码：1578 / 1580

页数：3

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