Larvicidal and growth inhibition of the malaria vector Anopheles stephensi by triterpenes from Dysoxylum malabaricum and Dysoxylum beddomei

被引：59

作者：

Nathan, S. Senthil ^{[1
,2
]}

Hisham, A. ^{[3
]}

Jayakumar, G. ^{[4
]}

机构：

[1] Vivekanandha Coll W, Post Grad & Res Dev Biotechnol, Namakkal, Tamil Nadu, India

[2] RDA, NICS, HARI, Plant Environm Div, Iksan 570080, Chonbuck, South Korea

[3] Sultan Qaboos Univ, Dept Chem, Coll Sci, Alkhode 123, Oman

[4] NSS Coll, Dept Chem, Cherthala, Kerala, India

来源：

FITOTERAPIA | 2008年 / 79卷 / 02期

关键词：

Dysoxylum malabaricum; Dysoxylum beddomei; Anopheles stephensi; larvicidal activity;

D O I：

10.1016/j.fitote.2007.07.013

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Secondary metabolites from Dysoxylum malabaricum and Dysoxylum beddomei were tested against mature and immature stage of the mosquito vector Anopheles stephensi under laboratory conditions. The triterpenes 3 beta,24,25-trihydroxycycloartane and beddomeilactone from D. malabaricum and D. beddomei showed strong larvicidal, pupicidal and adulticidal activity. They also affected the reproductive potential of adults by acting as oviposition deterrents. The highest concentration tested (10 ppm) of both compounds evoked more than 90% mortality and oviposition deterrence. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：106 / 111

页数：6

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