MR/PET Imaging of the Cardiovascular System

被引:63
作者
Robson, Philip M. [1 ]
Dey, Damini [2 ]
Newby, David E. [3 ]
Berman, Daniel [4 ,5 ]
Li, Debiao [2 ]
Fayad, Zahi A. [1 ]
Dweck, Marc R. [3 ]
机构
[1] Icahn Sch Med Mt Sinai, Translat & Mol Imaging Inst, New York, NY 10029 USA
[2] Cedars Sinai Med Ctr, Biomed Imaging Res Inst, Los Angeles, CA 90048 USA
[3] Univ Edinburgh, British Heart Fdn Ctr Cardiovasc Sci, Edinburgh, Midlothian, Scotland
[4] Cedars Sinai Med Ctr, Dept Imaging, Los Angeles, CA 90048 USA
[5] Cedars Sinai Med Ctr, Dept Med, Los Angeles, CA 90048 USA
基金
美国国家卫生研究院; 英国惠康基金;
关键词
atherosclerosis; cardiomyopathy; hybrid imaging; MR; PET; POSITRON-EMISSION-TOMOGRAPHY; CONTRAST-ENHANCED MRI; RISK PLAQUE FEATURES; MOTION CORRECTION; ATHEROSCLEROTIC PLAQUES; ATTENUATION CORRECTION; F-18-FDG PET; CARDIAC SARCOIDOSIS; AORTIC-STENOSIS; CAROTID PLAQUE;
D O I
10.1016/j.jcmg.2017.07.008
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiovascular imaging has largely focused on identifying structural, functional, and metabolic changes in the heart. The ability to reliably assess disease activity would have major potential clinical advantages, including the identification of early disease, differentiating active from stable conditions, and monitoring disease progression or response to therapy. Positron emission tomography (PET) imaging now allows such assessments of disease activity to be acquired in the heart, whereas magnetic resonance (MR) scanning provides detailed anatomic imaging and tissue characterization. Hybrid MR/PET scanners therefore combine the strengths of 2 already powerful imaging modalities. Simultaneous acquisition of the 2 scans also provides added benefits, including improved scanning efficiency, motion correction, and partial volume correction. Radiation exposure is lower than with hybrid PET/computed tomography scanning, which might be particularly beneficial in younger patients who may need repeated scans. The present review discusses the expanding clinical literature investigating MR/PET imaging, highlights its advantages and limitations, and explores future potential applications. (C) 2017 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.
引用
收藏
页码:1165 / 1179
页数:15
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