Lung inflammation in the pathogenesis of rheumatoid arthritis

被引：29

作者：

Demoruelle, M. Kristen ^{[1
]}

Wilson, Timothy M. ^{[1
]}

Deane, Kevin D. ^{[1
,2
]}

机构：

[1] Univ Colorado Denver, Div Rheumatol, Aurora, CO USA

[2] Denver Vet Affairs Med Ctr, Denver, CO USA

来源：

IMMUNOLOGICAL REVIEWS | 2020年 / 294卷 / 01期

关键词：

anti-citrullinated protein antibodies; lung; rheumatoid arthritis; rheumatoid factor; CITRULLINATED PROTEIN ANTIBODIES; RISK-FACTORS; PEPTIDE ANTIBODIES; PULMONARY-DISEASE; AUTOANTIBODIES; ONSET; AUTOIMMUNITY; MECHANISMS; MORTALITY; MODEL;

D O I：

10.1111/imr.12842

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The primary manifestation of rheumatoid arthritis (RA) is articular disease; however, extra-articular disease can also occur. In particular, pulmonary disease is a leading cause of morbidity and mortality in individuals with RA. Herein, we will review the types, prevalence, risk factors, and potential pathophysiology of lung disease in individuals with established RA. We will also discuss the emerging understanding of potential role of the lung in the generation of RA-related autoantibodies during a period of disease development termed "pre-RA." Finally, we will discuss a research agenda outlining the next steps to improve our understanding and management of lung inflammation and lung disease throughout the natural history of RA.

引用

页码：124 / 132

页数：9

共 97 条

[1] 2010 Rheumatoid Arthritis Classification Criteria An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative [J].

Aletaha, Daniel ;

Neogi, Tuhina ;

Silman, Alan J. ;

Funovits, Julia ;

Felson, David T. ;

Bingham, Clifton O., III ;

Birnbaum, Neal S. ;

Burmester, Gerd R. ;

Bykerk, Vivian P. ;

Cohen, Marc D. ;

Combe, Bernard ;

Costenbader, Karen H. ;

Dougados, Maxime ;

Emery, Paul ;

Ferraccioli, Gianfranco ;

Hazes, Johanna M. W. ;

Hobbs, Kathryn ;

Huizinga, Tom W. J. ;

Kavanaugh, Arthur ;

Kay, Jonathan ;

Kvien, Tore K. ;

Laing, Timothy ;

Mease, Philip ;

Menard, Henri A. ;

Moreland, Larry W. ;

Naden, Raymond L. ;

Pincus, Theodore ;

Smolen, Josef S. ;

Stanislawska-Biernat, Ewa ;

Symmons, Deborah ;

Tak, Paul P. ;

Upchurch, Katherine S. ;

Vencovsky, Jiri ;

Wolfe, Frederick ;

Hawker, Gillian .

ARTHRITIS AND RHEUMATISM, 2010, 62 (09) :2569-2581

[2] Prevalence and Incidence of Upper Respiratory Tract Infection Events Are Elevated Prior to the Development of Rheumatoid Arthritis in First-Degree Relatives [J].

Arleevskaya, Marina I. ;

Albina, Shafigullina ;

Larionova, Regina V. ;

Gabdoulkhakova, Aida G. ;

Lemerle, Julie ;

Renaudineau, Yves .

FRONTIERS IN IMMUNOLOGY, 2018, 9

[3] THE AMERICAN-RHEUMATISM-ASSOCIATION 1987 REVISED CRITERIA FOR THE CLASSIFICATION OF RHEUMATOID-ARTHRITIS [J].

ARNETT, FC ;

EDWORTHY, SM ;

BLOCH, DA ;

MCSHANE, DJ ;

FRIES, JF ;

COOPER, NS ;

HEALEY, LA ;

KAPLAN, SR ;

LIANG, MH ;

LUTHRA, HS ;

MEDSGER, TA ;

MITCHELL, DM ;

NEUSTADT, DH ;

PINALS, RS ;

SCHALLER, JG ;

SHARP, JT ;

WILDER, RL ;

HUNDER, GG .

ARTHRITIS AND RHEUMATISM, 1988, 31 (03) :315-324

[4] Interstitial lung disease in rheumatoid arthritis [J].

Ascherman D.P. .

Current Rheumatology Reports, 2010, 12 (5) :363-369

[5] Morphologic and quantitative assessment of CD20+ B cell infiltrates in rheumatoid arthritis-associated nonspecific interstitial pneumonia and usual interstitial pneumonia [J].

Atkins, SR ;

Turesson, C ;

Myers, JL ;

Tazelaar, HD ;

Ryu, JH ;

Matteson, EL ;

Bongartz, T .

ARTHRITIS AND RHEUMATISM, 2006, 54 (02) :635-641

[6] Anti-Citrullinated Protein Antibodies in Unaffected First-Degree Relatives of Rheumatoid Arthritis Patients [J].

Barra, Lillian ;

Scinocca, Mathias ;

Saunders, Sheri ;

Bhayana, Rajesh ;

Rohekar, Sherry ;

Racape, Maud ;

Coles, Robert ;

Cairns, Ewa ;

Bell, David A. .

ARTHRITIS AND RHEUMATISM, 2013, 65 (06) :1439-1447

[7] Rheumatoid arthritis-associated autoantibodies and subclinical interstitial lung disease: the Multi-Ethnic Study of Atherosclerosis [J].

Bernstein, Elana J. ;

Barr, R. Graham ;

Austin, John H. M. ;

Kawut, Steven M. ;

Raghu, Ganesh ;

Sell, Jessica L. ;

Hoffman, Eric A. ;

Newell, John D., Jr. ;

Watts, Jubal R., Jr. ;

Nath, Hrudaya ;

Sonavane, Sushil K. ;

Bathon, Joan M. ;

Majka, Darcy S. ;

Lederer, David J. .

THORAX, 2016, 71 (12) :1082-1090

[8] Incidence and Mortality of Interstitial Lung Disease in Rheumatoid Arthritis [J].

Bongartz, Tim ;

Nannini, Carlotta ;

Medina-Velasquez, Yimy F. ;

Achenbach, Sara J. ;

Crowson, Cynthia S. ;

Ryu, Jay H. ;

Vassallo, Robert ;

Gabriel, Sherine E. ;

Matteson, Eric L. .

ARTHRITIS AND RHEUMATISM, 2010, 62 (06) :1583-1591

[9] Rheumatoid Arthritis-Associated Interstitial Lung Disease: Current Concepts [J].

Brito, Yoel ;

Glassberg, Marilyn K. ;

Ascherman, Dana P. .

CURRENT RHEUMATOLOGY REPORTS, 2017, 19 (12)

[10] Microbiome and mucosal inflammation as extra-articular triggers for rheumatoid arthritis and autoimmunity [J].

Brusca, Samuel B. ;

Abramson, Steven B. ;

Scher, Jose U. .

CURRENT OPINION IN RHEUMATOLOGY, 2014, 26 (01) :101-107

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