Immediate hypersensitivity to low molecular weight heparins: Remarks concerning a case

被引：1

作者：

Sacre, A. ^{[1
]}

Brasseur, M. ^{[2
]}

Boulet, D. ^{[3
]}

Halloy, J. -L. ^{[4
]}

机构：

[1] CHR St Joseph Warquignies, Serv Pneumol, Mons, Belgium

[2] Hop Ambroise Pare, Lab Serv, Mons, Belgium

[3] CHR St Joseph Warquignies, Serv Hematooncol, Dept Med Interne, Mons, Belgium

[4] CHR St Joseph Warquignies, Serv Pneumoallergol, Mons, Belgium

来源：

REVUE FRANCAISE D ALLERGOLOGIE | 2010年 / 50卷 / 06期

关键词：

Heparin; Drug allergy; Immediate hypersensitivity; Basophil activation test; DELAYED-TYPE HYPERSENSITIVITY; DIAGNOSIS; ALLERGY;

D O I：

10.1016/j.reval.2010.03.008

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Heparin is one of the oldest drugs on the market. Widely used for the prevention and treatment of thromboembolic diseases, its adverse effects are well-known. Allergic reactions are rare (0.2%), especially immediate hypersensitivity reactions, which are exceptional. We report a case of an immediate allergic reaction to nadroparine. We discuss diagnostic methods, the potential interest in the basophile activation test, cross-reactivity and therapeutic alternatives. (C) 2010 Elsevier Masson SAS. All rights reserved.

引用

页码：509 / 512

页数：4

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