Anti-diarrhoeal activity of Butea monosperma in experimental animals

被引:38
作者
Gunakkunru, A
Padmanaban, K
Thirumal, P
Pritila, J
Parimala, G
Vengatesan, N
Gnanasekar, N
Perianayagam, JB
Sharma, SK [1 ]
Pillai, KK
机构
[1] Guru Jambheshwar Univ, Fac Pharmaceut Sci, Phytochem & Pharmacognosy Div, Hisar 125001, Haryana, India
[2] KP Coll Pharm, Dept Pharmacol, Thiruvannamalai, India
[3] Jamia Hamdard Hamdard Univ, Dept Pharmacol, Fac Pharm, New Delhi 110062, India
关键词
Butea monosperma; Fabaceae; anti-diarrhoeal; intestinal secretion; gastrointestinal motility;
D O I
10.1016/j.jep.2004.12.021
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The anti-diarrhoeal potential of the ethanolic extract of stern bark of Butea monosperma (Lam) Kuntz has been evaluated using several experimental models in Wistar albino rats. The extract inhibited castor oil induced diarrhoea and PGE(2) induced enteropooling in rats; it also reduced gastrointestinal motility after charcoal meal administration. The results obtained establish the efficacy and substantiate the use of this herbal remedy as a non-specific treatment for diarrhoea in folk medicine. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:241 / 244
页数:4
相关论文
共 18 条
[1]   EFFECTS OF OLEIC AND RICINOLEIC ACIDS ON NET JEJUNAL WATER AND ELECTROLYTE MOVEMENT - PERFUSION STUDIES IN MAN [J].
AMMON, HV ;
THOMAS, PJ ;
PHILLIPS, SF .
JOURNAL OF CLINICAL INVESTIGATION, 1974, 53 (02) :374-379
[2]   DELAY OF CASTOR-OIL DIARRHEA IN RATS - NEW WAY TO EVALUATE INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS [J].
AWOUTERS, F ;
NIEMEGEERS, CJE ;
LENAERTS, FM ;
JANSSEN, PAJ .
JOURNAL OF PHARMACY AND PHARMACOLOGY, 1978, 30 (01) :41-45
[3]   AN ANTIFUNGAL CONSTITUENT FROM THE STEM BARK OF BUTEA-MONOSPERMA [J].
BANDARA, BMR ;
KUMAR, NS ;
SAMARANAYAKE, KMS .
JOURNAL OF ETHNOPHARMACOLOGY, 1989, 25 (01) :73-75
[4]   EFFECT OF RICINOLEIC ACID AND OTHER LAXATIVES ON NET WATER FLUX AND PROSTAGLANDIN-E RELEASE BY THE RAT COLON [J].
BEUBLER, E ;
JUAN, H .
JOURNAL OF PHARMACY AND PHARMACOLOGY, 1979, 31 (10) :681-685
[5]  
Chopra R. N., 1956, GLOSSARY INDIAN MED
[6]  
GAGINELLA TS, 1975, J PHARMACOL EXP THER, V195, P355
[7]  
Gnanasekar N., 2004, Indian Journal of Pharmacology, V36, P177
[8]  
JAYAWEERA DMA, 1981, MED PLANT USED CEY 3, P161
[9]  
JOUSILAHTI P, 1977, PUBLIC HLTH, V111, P5
[10]  
LUDERER JR, 1980, ADV PROSTAGLANDIN TH, P1633