Multicentric reticulohistiocytosis: report of a case with systemic disease

被引:2
作者
Stock, N
Saikali, S
Chevrant-Breton, J
Leroy, JP
Le Gall, F
机构
[1] CHU Pontchaillou, Dept Pathol Anat, F-35033 Rennes, France
[2] CHU Pontchaillou, Dermatol Serv, F-35000 Rennes, France
[3] CHU Morvan, Anat Pathol Lab, F-29000 Brest, France
关键词
multicentric reticulohistiocytosis; non Langherhans histiocytosis; immunohistochemistry; electron microscopy;
D O I
10.1016/S0242-6498(05)80099-9
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Multicentric reticulohistiocytosis (RHM) is a rare non Langherhans cell histiocytosis with skin and joint involvment. Nearly all organs can be involved. Association with cancer occurs in about 25% of cases. Association with auto-immune diseases has also been recorded. Microscopic examination Shows a histiocytic nodular infiltrate made of giant cells with ground-glass appearance and PAS positive cytoplasm. Immunostaining shows cell positivity for CD68 and negativity for CD1a and S100 protein. No Birbeck granules are found at ultrostructural examination.
引用
收藏
页码:50 / 53
页数:4
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