A sensitive voltammetric morphine nanosensor based on BaFe12O19 nanoparticle-modified screen-printed electrodes

被引：10

作者：

Bagherinasab, Zoheira ^{[1
]}

Beitollahi, Hadi ^{[2
]}

Yousefi, Mohammad ^{[3
]}

Bagherzadeh, Mojtaba ^{[4
]}

Hekmati, Malak ^{[5
]}

机构：

[1] Islamic Azad Univ, Dept Chem, Sci & Res Branch, Tehran, Iran

[2] Grad Univ Adv Technol, Inst Sci & High Technol & Environm Sci, Environm Dept, Kerman, Iran

[3] Islamic Azad Univ, Dept Chem, Yadegar E Imam Khomeyni RAH Shar E Rey Branch, Tehran, Iran

[4] Sharif Univ Technol, Dept Chem, Tehran, Iran

[5] Islamic Azad Univ, Fac Pharmaceut Chem, Dept Organ Chem, Tehran Med Sci, Tehran, Iran

来源：

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2020年 / 17卷 / 03期

关键词：

BaFe12O19; nanoparticles; Morphine; Modified electrode; Voltammetric techniques; GLASSY-CARBON ELECTRODE; LIQUID-CHROMATOGRAPHIC DETERMINATION; ELECTROCHEMICAL SENSOR; PASTE ELECTRODE; AMPEROMETRIC DETECTION; BIOLOGICAL SAMPLES; NANOCOMPOSITE; ACETAMINOPHEN; NANOTUBES; BIOSENSOR;

D O I：

10.1007/s13738-019-01808-x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Morphine is a strong opioid used for the treatment of moderate to severe pain. Its use is, however, associated with adverse effects including sedation, nausea, constipation, respiratory depression, and development of tolerance as well as dependence. Thus, in this work electrochemical oxidation of morphine has been done on BaFe12O19 nanoparticles of the modified electrode. BaFe12O19 nanoparticles of the modified graphite screen-printed electrode (GSPE) and the bare GSPE were compared, representing that the modified electrode takes advantages of higher sensitivities and selectivities with lower limit of detection. Differential pulse voltammetric procedure has been used to analyze data. Results indicated that linear response range and determination limit, respectively, are 0.06-600.0 mu M and 0.02 mu M. The modified electrode has been substantially applied to determine morphine in real specimens with acceptable outputs.

引用

页码：717 / 724

页数：8

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