A facile synthesis of (R)-3-amino-4-phenylbutyric acid from L-aspartic acid

被引：4
作者：
Seki, M
Matsumoto, K
机构：
[1] Lead Optimization Research Lahoratory, Tanahe Seiyaku Co, Osaka, 532, 16-89, Kashima 3-chome, Yodogmra-ku
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1996年 / 60卷 / 05期
关键词：
beta-amino acid; L-aspartic acid; 4-phenyl-3-aminobutyric acid; Friedel-Crafts acylation; alpha-aminoketone;
D O I：
10.1271/bbb.60.916
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A practical synthesis of (R)-3-amino-4-phenylbutyric acid 1, based on Friedel-Crafts acylation with the alpha-aminocarboxyl group of L-aspartic acid retaining its original alpha-carbon chirality, is described.
引用
收藏
页码：916 / 917
页数：2
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