Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity

被引：40

作者：

Messali, Mouslim ^{[1
]}

机构：

[1] Taibah Univ, Dept Chem, Al Madina Al Mounawara 30002, Saudi Arabia

来源：

MOLECULES | 2015年 / 20卷 / 08期

关键词：

eco-friendly synthesis; ultrasound irradiation; ionic liquid; antimicrobial activity; ANTIBACTERIAL ACTIVITY; IMIDAZOLIUM; SOLVENTS; TOXICITY;

D O I：

10.3390/molecules200814936

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The present study reports a green synthesis of a new family of ionic liquids (ILs) based on functionalized 4-dimethylaminopyridinium derivatives. The structures of 23 newly synthesized ILs (2-24) were confirmed by FT-IR, H-1-, C-13-, B-11-, F-19-, and P-31-NMR spectroscopy and mass spectrometry. The antimicrobial activity of all novel ILs was tested against a panel of bacteria and fungi. The results prove that all tested ILs are effective antibacterial and antifungal agents, especially 4-(dimethylamino)-1-(4-phenoxybutyl)pyridinium derivatives 5 and 19.

引用

页码：14936 / 14949

页数：14

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