Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity

被引：40
|
作者：
Messali, Mouslim [1 ]
机构：
[1] Taibah Univ, Dept Chem, Al Madina Al Mounawara 30002, Saudi Arabia
来源：
MOLECULES | 2015年 / 20卷 / 08期
关键词：
eco-friendly synthesis; ultrasound irradiation; ionic liquid; antimicrobial activity; ANTIBACTERIAL ACTIVITY; IMIDAZOLIUM; SOLVENTS; TOXICITY;
D O I：
10.3390/molecules200814936
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The present study reports a green synthesis of a new family of ionic liquids (ILs) based on functionalized 4-dimethylaminopyridinium derivatives. The structures of 23 newly synthesized ILs (2-24) were confirmed by FT-IR, H-1-, C-13-, B-11-, F-19-, and P-31-NMR spectroscopy and mass spectrometry. The antimicrobial activity of all novel ILs was tested against a panel of bacteria and fungi. The results prove that all tested ILs are effective antibacterial and antifungal agents, especially 4-(dimethylamino)-1-(4-phenoxybutyl)pyridinium derivatives 5 and 19.
引用
收藏
页码：14936 / 14949
页数：14
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