State of the Science and Future Directions for Liquid Biopsies in Drug Development

被引：9

作者：

Narayan, Preeti ^{[1
]}

Ghosh, Soma ^{[2
]}

Philip, Reena ^{[2
]}

Barrett, J. Carl ^{[3
]}

McCormack, Robert T. ^{[4
]}

Odegaard, Justin I. ^{[5
]}

R. Oxnard, Geoffrey ^{[6
]}

Pracht, Laurel J. ^{[7
]}

Williams, P. Mickey ^{[8
]}

Kelloff, Gary J. ^{[7
]}

Beaver, Julia A. ^{[1
]}

机构：

[1] US FDA, Ctr Drug Evaluat & Res, WO22 Room 2331,10903 New Hampshire Ave, Silver Spring, MD 20993 USA

[2] US FDA, Ctr Devices & Radiol Hlth, Silver Spring, MD USA

[3] AstraZeneca, Waltham, MA USA

[4] RMCC Consulting LLC, Chester, NJ USA

[5] Guardant Hlth, Redwood City, MA USA

[6] Harvard Univ, Dana Farber Canc Inst, Boston, MA 02115 USA

[7] NCI, Bethesda, MD 20892 USA

[8] Frederick Natl Labs Canc Res, Frederick, MD USA

来源：

ONCOLOGIST | 2020年 / 25卷 / 09期

关键词：

CIRCULATING TUMOR DNA;

D O I：

10.1634/theoncologist.2020-0246

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

With advances in precision oncology, liquid biopsies have shown promise as a minimally invasive means to diagnose cancer and guide treatment decisions. This commentary presents an assessment of the potential and the challenges of widespread use of liquid biopsy testing, based on the 2019 Accelerating Anticancer Agent Development Workshop.

引用

页码：730 / 732

页数：3

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