State of the Science and Future Directions for Liquid Biopsies in Drug Development

被引：9

作者：

Narayan, Preeti ^{[1
]}

Ghosh, Soma ^{[2
]}

Philip, Reena ^{[2
]}

Barrett, J. Carl ^{[3
]}

McCormack, Robert T. ^{[4
]}

Odegaard, Justin I. ^{[5
]}

R. Oxnard, Geoffrey ^{[6
]}

Pracht, Laurel J. ^{[7
]}

Williams, P. Mickey ^{[8
]}

Kelloff, Gary J. ^{[7
]}

Beaver, Julia A. ^{[1
]}

机构：

[1] US FDA, Ctr Drug Evaluat & Res, WO22 Room 2331,10903 New Hampshire Ave, Silver Spring, MD 20993 USA

[2] US FDA, Ctr Devices & Radiol Hlth, Silver Spring, MD USA

[3] AstraZeneca, Waltham, MA USA

[4] RMCC Consulting LLC, Chester, NJ USA

[5] Guardant Hlth, Redwood City, MA USA

[6] Harvard Univ, Dana Farber Canc Inst, Boston, MA 02115 USA

[7] NCI, Bethesda, MD 20892 USA

[8] Frederick Natl Labs Canc Res, Frederick, MD USA

来源：

ONCOLOGIST | 2020年 / 25卷 / 09期

关键词：

CIRCULATING TUMOR DNA;

D O I：

10.1634/theoncologist.2020-0246

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

With advances in precision oncology, liquid biopsies have shown promise as a minimally invasive means to diagnose cancer and guide treatment decisions. This commentary presents an assessment of the potential and the challenges of widespread use of liquid biopsy testing, based on the 2019 Accelerating Anticancer Agent Development Workshop.

引用

页码：730 / 732

页数：3

共 13 条

[1] Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution [J].

Abbosh, Christopher ;

Birkbak, Nicolai J. ;

Wilson, Gareth A. ;

Jamal-Hanjani, Mariam ;

Constantin, Tudor ;

Salari, Raheleh ;

Le Quesne, John ;

Moore, David A. ;

Veeriah, Selvaraju ;

Rosenthal, Rachel ;

Marafioti, Teresa ;

Kirkizlar, Eser ;

Watkins, Thomas B. K. ;

McGranahan, Nicholas ;

Ward, Sophia ;

Martinson, Luke ;

Riley, Joan ;

Fraioli, Francesco ;

Al Bakir, Maise ;

Gronroos, Eva ;

Zambrana, Francisco ;

Endozo, Raymondo ;

Bi, Wenya Linda ;

Fennessy, Fiona M. ;

Sponer, Nicole ;

Johnson, Diana ;

Laycock, Joanne ;

Shafi, Seema ;

Czyzewska-Khan, Justyna ;

Rowan, Andrew ;

Chambers, Tim ;

Matthews, Nik ;

Turajlic, Samra ;

Hiley, Crispin ;

Lee, Siow Ming ;

Forster, Martin D. ;

Ahmad, Tanya ;

Falzon, Mary ;

Borg, Elaine ;

Lawrence, David ;

Hayward, Martin ;

Kolvekar, Shyam ;

Panagiotopoulos, Nikolaos ;

Janes, Sam M. ;

Thakrar, Ricky ;

Ahmed, Asia ;

Blackhall, Fiona ;

Summers, Yvonne ;

Hafez, Dina ;

Naik, Ashwini .

NATURE, 2017, 545 (7655) :446-+

[2]

[Anonymous], PREM APPR PMA COB EG

[3]

[Anonymous], THER PIK3CA RGQ PCR

[4] Next-Generation Sequencing of Circulating Tumor DNA for Early Cancer Detection [J].

Aravanis, Alexander M. ;

Lee, Mark ;

Klausner, Richard D. .

CELL, 2017, 168 (04) :571-574

[5] Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer [J].

Garcia-Murillas, Isaac ;

Schiavon, Gaia ;

Weigelt, Britta ;

Ng, Charlotte ;

Hrebien, Sarah ;

Cutts, Rosalind J. ;

Cheang, Maggie ;

Osin, Peter ;

Nerurkar, Ashutosh ;

Kozarewa, Iwanka ;

Garrido, Javier Armisen ;

Dowsett, Mitch ;

Reis-Filho, Jorge S. ;

Smith, Ian E. ;

Turner, Nicholas C. .

SCIENCE TRANSLATIONAL MEDICINE, 2015, 7 (302)

[6] Current and future perspectives of liquid biopsies in genomics-driven oncology [J].

Heitzer, Ellen ;

Haque, Imran S. ;

Roberts, Charles E. S. ;

Speicher, Michael R. .

NATURE REVIEWS GENETICS, 2019, 20 (02) :71-88

[7] Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review [J].

Merker, Jason D. ;

Oxnard, Geoffrey R. ;

Compton, Carolyn ;

Diehn, Maximilian ;

Hurley, Patricia ;

Lazar, Alexander J. ;

Lindeman, Neal ;

Lockwood, Christina M. ;

Rai, Alex J. ;

Schilsky, Richard L. ;

Tsimberidou, Apostolia M. ;

Vasalos, Patricia ;

Billman, Brooke L. ;

Oliver, Thomas K. ;

Bruinooge, Suanna S. ;

Hayes, Daniel F. ;

Turner, Nicholas C. .

JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (16) :1631-+

[8] Considerations in the development of circulating tumor cell technology for clinical use [J].

Parkinson, David R. ;

Dracopoli, Nicholas ;

Petty, Brenda Gumbs ;

Compton, Carolyn ;

Cristofanilli, Massimo ;

Deisseroth, Albert ;

Hayes, Daniel F. ;

Kapke, Gordon ;

Kumar, Prasanna ;

Lee, Jerry S. H. ;

Liu, Minetta C. ;

McCormack, Robert ;

Mikulski, Stanislaw ;

Nagahara, Larry ;

Pantel, Klaus ;

Pearson-White, Sonia ;

Punnoose, Elizabeth A. ;

Roadcap, Lori T. ;

Schade, Andrew E. ;

Scher, Howard I. ;

Sigman, Caroline C. ;

Kelloff, Gary J. .

JOURNAL OF TRANSLATIONAL MEDICINE, 2012, 10

[9] Promises and Pitfalls of Using Liquid Biopsy for Precision Medicine [J].

Rossi, Giovanna ;

Ignatiadis, Michail .

CANCER RESEARCH, 2019, 79 (11) :2798-2804

[10] How liquid biopsies can change clinical practice in oncology [J].

Siravegna, G. ;

Mussolin, B. ;

Venesio, T. ;

Marsoni, S. ;

Seoane, J. ;

Dive, C. ;

Papadopoulos, N. ;

Kopetz, S. ;

Corcoran, R. B. ;

Siu, L. L. ;

Bardelli, A. .

ANNALS OF ONCOLOGY, 2019, 30 (10) :1580-1590

← 1 2 →