Racial disparities and human papillomavirus status in oropharyngeal cancer: A systematic review and meta-analysis

被引：18
|
作者：
Lenze, Nicholas R. [1 ]
Farquhar, Douglas R. [1 ]
Mazul, Angela L. [2 ]
Masood, Maheer M. [1 ]
Zevallos, Jose P. [3 ]
机构：
[1] Univ N Carolina, Sch Med, Dept Otolaryngol Head & Neck Surg, Chapel Hill, NC 27515 USA
[2] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27515 USA
[3] Washington Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, 660 S Euclid Ave,Campus Box 8115, St Louis, MO 63110 USA
来源：
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2019年 / 41卷 / 01期
关键词：
health status disparities; human papillomavirus; meta-analysis; oropharyngeal cancer; survival; SQUAMOUS-CELL CARCINOMA; UNITED-STATES; NECK-CANCER; AFRICAN-AMERICANS; ORAL-CAVITY; HEAD; SURVIVAL; OUTCOMES; IMPACT; RACE;
D O I：
10.1002/hed.25414
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Background This study used a meta-analysis to quantify the degree to which the racial disparity in overall survival for black versus white Americans with oropharyngeal squamous cell carcinoma (OPSCC) persists after adjusting for human papillomavirus (HPV) status. Methods PubMed/MEDLINE, Cochrane Database of Systematic Reviews, and CINAHLA were searched through November 2017. The PRISMA statement was followed. The pooled hazard ratio (HR) was calculated using a random-effects model. Results Five studies met the inclusion criteria and had suitable data for pooling into the meta-analysis (N = 1153). The pooled HR for overall survival in black versus white Americans with OPSCC after adjusting for HPV status was calculated to be 1.45 (95% confidence interval, 0.87-2.40). Conclusions The difference in survival for black versus white Americans with OPSCC is not significant after adjusting for HPV status but still trends in the direction of a disparity. Additional studies are needed to better characterize this disparity.
引用
收藏
页码：256 / 261
页数：6
相关论文
共 50 条
  • [1] Systematic review and meta-analysis of racial survival disparities among oropharyngeal cancer cases byHPVstatus
    Stein, Eva
    Lenze, Nicholas R.
    Yarbrough, Wendell G.
    Hayes, D. Neil
    Mazul, Angela
    Sheth, Siddharth
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2020, 42 (10): : 2985 - 3001
  • [2] Characteristics of human papillomavirus infection among oropharyngeal cancer patients: A systematic review and meta-analysis
    Cui, Meimei
    Cheng, Jinling
    Cheng, Huijuan
    Zhao, Ming
    Zhou, Dan
    Zhang, Min
    Jia, Jingjing
    Luo, Limei
    ARCHIVES OF ORAL BIOLOGY, 2024, 157
  • [3] Sex and human papillomavirus in oropharyngeal cancer: A systematic review and meta-analysis
    Marrero-Gonzalez, Alejandro R.
    Chernov, Evan S.
    Nguyen, Shaun A.
    Keith, Brian A.
    Stevens, Madelyn N.
    Kejner, Alexandra E.
    AMERICAN JOURNAL OF OTOLARYNGOLOGY, 2024, 45 (06)
  • [4] Sexual history of patients with human papillomavirus positive and negative oropharyngeal cancer: A systematic review and meta-analysis
    Durrant, Frederick G.
    Gutierrez III, Jorge A.
    Nguyen, Shaun A.
    Nathan, Cherie-Ann O.
    Newman, Jason G.
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2024, 46 (10): : 2473 - 2483
  • [5] Predictive value of human papillomavirus in oropharyngeal carcinoma treated with radiotherapy: An updated systematic review and meta-analysis of 30 trials
    Petrelli, Fausto
    Sarti, Enrico
    Barni, Sandro
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2014, 36 (05): : 750 - 759
  • [6] Association of Salivary Human Papillomavirus Infection and Oral and Oropharyngeal Cancer: A Meta-Analysis
    Rapado-Gonzalez, Oscar
    Martinez-Reglero, Cristina
    Salgado-Barreira, Angel
    Rodriguez-Fernandez, Almudena
    Aguin-Losada, Santiago
    Leon-Mateos, Luis
    Muinelo-Romay, Laura
    Lopez-Lopez, Rafael
    Mercedes Suarez-Cunqueiro, Maria
    JOURNAL OF CLINICAL MEDICINE, 2020, 9 (05)
  • [7] Racial disparities in incidence of human papillomavirus-associated oropharyngeal cancer in an urban population
    Ramer, Ilana
    Varier, Indu
    Zhang, David
    Demicco, Elizabeth G.
    Posner, Marshall R.
    Misiukiewicz, Krzysztof
    Genden, Eric M.
    Miles, Brett A.
    Teng, Marita S.
    Sikora, Andrew G.
    CANCER EPIDEMIOLOGY, 2016, 44 : 91 - 95
  • [8] Racial Disparities in Oropharyngeal Cancer Stage at Diagnosis
    Megwalu, Uchechukwu C.
    Ma, Yifei
    ANTICANCER RESEARCH, 2017, 37 (02) : 835 - 839
  • [9] Human papillomavirus related head and neck cancer survival: A systematic review and meta-analysis
    O'Rorke, M. A.
    Ellison, M. V.
    Murray, L. J.
    Moran, M.
    James, J.
    Anderson, L. A.
    ORAL ONCOLOGY, 2012, 48 (12) : 1191 - 1201
  • [10] The role of insurance status as a mediator of racial disparities in oropharyngeal cancer outcomes
    Shukla, Navika
    Ma, Yifei
    Megwalu, Uchechukwu C.
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2021, 43 (10): : 3116 - 3124
12345