Water-Soluble, Monodisperse, Lanthanide-Doped Y(Gd)VO4 Nanocrystals as Promising Multimodal Bioprobe

被引:15
作者
Chen, Cailing [1 ]
Li, Chunguang [1 ]
Li, Tao [1 ]
Liu, Jianhua [2 ]
Huang, He [1 ]
Bai, Tianyu [1 ]
Wang, Zhaorui [1 ]
Shi, Zhan [1 ]
Feng, Shouhua [1 ]
机构
[1] Jilin Univ, Coll Chem, State Key Lab Inorgan Synth & Preparat Chem, Changchun 130012, Peoples R China
[2] Jilin Univ, Hosp 2, Dept Radiol, Changchun 130022, Peoples R China
基金
中国国家自然科学基金;
关键词
Hydrothermal synthesis; Nanostructures; Biosensors; Luminescence; Vanadates; Lanthanides; UP-CONVERSION NANOCRYSTALS; OPTICAL SPECTROSCOPY; LUMINESCENT PROPERTIES; NANOPARTICLES; MULTICOLOR; SIZE; EU3+; TRANSPARENT; NANOPROBES; CARRIERS;
D O I
10.1002/ejic.201500212
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Monodisperse and water-soluble lanthanide (Ln(3+))-doped Y(Gd)VO4 nanocrystals (NCs) have been successfully synthesized by a fast, facile, and environmentally friendly microwave-assisted route with poly(acrylic acid) as the surfactant. The Y(Gd)VO4:5%Ln(3+) (Ln = Eu, Dy, Sm) NCs have unique fluorescence properties and polydimethylsiloxane (PDMS)-based white solid nanocomposites containing YVO4:5%Eu3+ NCs show red emission upon UV irradiation. GdVO4 NCs can act as CT and MRI contrast agents as a result of their magnetic and X-ray absorption properties. A layer of SiO2 was coated onto the surfaces of the nanoparticles and MTT assays were carried out to test the cytotoxicity of the YVO4@SiO2 and GdVO4 NCs. The results indicate that the Y(Gd)VO4 NCs have potential in multimodal optical/MRI/CT bio-imaging.
引用
收藏
页码:3108 / 3115
页数:8
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